SCHEMBL2524017

SCHEMBL2524017

CCCCN(CCCC)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
DNM1 Q05193 3/20 0.35
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
ALDH1A1 P00352 1/20 0.33
ALDH2 P05091 1/20 0.33
THRB P10828 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12243063 0.94 DNM1 (0.43) TSHRLMNADNM1CA12CA1
SCHEMBL7776810 0.94 DNM1 (0.32) TSHRLMNADNM1CA12CA1
SCHEMBL26502986 0.92 DNM1 (0.48) TSHRLMNADNM1CA12CA1
SCHEMBL26502982 0.92 DNM1 (0.48) TSHRLMNADNM1CA12CA1
SCHEMBL13152919 0.91 DNM1 (0.46) TSHRLMNADNM1CA12CA1
SCHEMBL10705836 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
Nonane SCHEMBL28466423 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL14997774 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL14997773 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL7770548 0.88 CA12 (0.33) TSHRLMNADNM1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 US disclosed
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 US disclosed
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-27 US disclosed
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-27 US disclosed
US-20230399290-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS PTC INNOVATIONS LLC (US) 2023-12-14 US disclosed
US-20230399292-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS PTC Innovations, LLC 2023-12-14 US disclosed
US-20230399291-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS PTC INNOVATIONS LLC (US) 2023-12-14 US disclosed
US-11814335-B1 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms PTC Innovations, LLC (US) 2023-11-14 US disclosed
CN-102884039-A Method for producing unsymmetrical secondary tert-butyl amines in the gas phase BASF SE 2013-01-16 CN disclosed
WO-2011124577-A1 METHOD FOR PRODUCING UNSYMMETRICAL SECONDARY TERT-BUTYL AMINES IN THE GAS PHASE BASF SE (DE) 2011-10-13 WO disclosed
US-20110251434-A1 PROCESS FOR PREPARING UNSYMMETRIC SECONDARY TERT-BUTYLAMINES IN THE GAS PHASE BASF SE (DE) 2011-10-13 US disclosed
US-20110229581-A1 RELEASABLE CATIONIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2011-09-22 US disclosed
US-7528163-B2 N,N-Dibutyl-2-[3-(2,2-dimethylpropanoyl)-6-methoxy-1H-indazol-1-yl]acetamide; potassium channel blocker; eye neuroprotectant; hypotensive agent; glaucoma, intraoccular pressure in the eye MERCK & CO. INC. (US) 2009-05-05 US disclosed
US-7365093-B2 Endothelin antagonists ABBOTT LABORATORIES (US) 2008-04-29 US disclosed
US-7208517-B1 Endothelin antagonists ABBOTT LABORTORIES (US) 2007-04-24 US disclosed
EP-0838508-B1 Aqueous ink composition for use in an ink-jet printer SEIKO EPSON CORP (JP) 2001-08-29 EP disclosed
US-5871572-A COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID SEIKO EPSON CORPORATION (JP) 1999-02-16 US disclosed
EP-0838508-A2 Aqueous ink composition for use in an ink-jet printer SEIKO EPSON CORPORATION (JP) 1998-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251434-A1 PROCESS FOR PREPARING UNSYMMETRIC SECONDARY TERT-BUTYLAMINES IN THE GAS PHASE TERT, PNMT, ADH5 TSHR 1149/4885LMNA 798/4885DNM1 3857/4885
US-20230399290-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS OPRK1, ACHE, F5 TSHR 2954/4885LMNA 2285/4885DNM1 4100/4885
US-20230399292-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS OPRM1, OPRL1, OPRK1 TSHR 1465/4885LMNA 2668/4885DNM1 2591/4885
US-20230399291-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS CHRM2, RXFP2, OPRM1 TSHR 2336/4885LMNA 3130/4885DNM1 2355/4885
US-20110229581-A1 RELEASABLE CATIONIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS APLNR, LPAR6, ABHD16A TSHR 2121/4885LMNA 467/4885DNM1 448/4885
US-11814335-B1 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms F8, F5, OPRM1 TSHR 2702/4885LMNA 2286/4885DNM1 4333/4885
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 TSHR 2262/4885LMNA 350/4885DNM1 307/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 TSHR 3323/4885LMNA 284/4885DNM1 487/4885
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS PNLIP, LIPA, PHOSPHO1 TSHR 2016/4885LMNA 164/4885DNM1 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.