SCHEMBL25253907

SCHEMBL25253907

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Sc3ccccc3OCC(=O)O)c(Cl)cc2F)c1=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
PTGDR2 Q9Y5Y4 7/20 0.35
PPARG P37231 3/20 0.34
PPARD Q03181 3/20 0.34
PPARA Q07869 3/20 0.34
RORC P51449 1/20 0.33
PKM P14618 1/20 0.33
SLC6A9 P48067 4/20 0.33
BCAT2 O15382 1/20 0.32
BCAT1 P54687 1/20 0.32
THRB P10828 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27044941 0.93 LMNA (0.33) MEN1LMNAKMT2ABCAT2BCAT1
SCHEMBL27047407 0.90 PKM (0.35) LMNAPTGDR2PPARGPPARDPPARA
SCHEMBL29452544 0.88 PPOX (0.33) MEN1LMNAKMT2APPARGPPARD
SCHEMBL27044932 0.88 PPOX (0.33) MEN1LMNAKMT2APPARGPPARD
SCHEMBL29709398 0.88 PKM (0.34) PPARGPPARDPPARAPKM
SCHEMBL27047411 0.88 BCAT2 (0.39) PTGDR2PPARGPPARDPPARABCAT2
SCHEMBL27047417 0.87 ALDH1A1 (0.36) MEN1LMNAKMT2APTGDR2
SCHEMBL29452833 0.86 DHODH (0.35) LMNAKMT2APTGDR2PPARGBCAT2
SCHEMBL25295816 0.86 DHODH (0.35) LMNAKMT2APTGDR2PPARGBCAT2
SCHEMBL3245244 0.85 BCAT1 (0.39) MEN1LMNAKMT2APTGDR2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2026-05-21 US disclosed
EP-4602036-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2025-08-20 EP disclosed
CN-120035584-A Substituted N-phenyluracils and salts thereof and their use as herbicidal agents 拜耳公司 2025-05-23 CN disclosed
EP-4200282-B1 SUBSTITUTED N-PHENYLURACILS AS WELL AS THEIR SALTS AND THEIR USE AS HERBICIDES. BAYER AG (DE) 2024-09-11 EP disclosed
WO-2024078906-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 WO disclosed
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
EP-4200282-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-06-28 EP disclosed
WO-2022043205-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2022-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES CBR1, CBR3, HDHD5 MEN1 4233/4885LMNA 2296/4885KMT2A 2946/4885
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES PFAS, DDT, NOTUM MEN1 4557/4885LMNA 3856/4885KMT2A 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.