Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094588 | 0.84 | ADRB2 (0.60) | HTR6MTNR1AHTR2AHTR2CPPARG | |
| SCHEMBL25180278 | 0.83 | HTR6 (0.46) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL25329812 | 0.75 | HTR6 (0.70) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL23608111 | 0.71 | HTR7 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL27614855 | 0.70 | MTNR1A (0.55) | HTR6MTNR1APPARGPPARDPPARA | |
| SCHEMBL6830010 | 0.70 | ADRB2 (0.58) | HTR6MTNR1AHTR2AHTR2CPPARG | |
| SCHEMBL30859492 | 0.69 | HTR6 (0.75) | HTR6MTNR1AHTR1ADRD2HTR1D | |
| SCHEMBL24877632 | 0.69 | HTR6 (0.75) | HTR6MTNR1AHTR1ADRD2HTR1D | |
| SCHEMBL25242394 | 0.68 | HTR6 (0.60) | HTR6MTNR1AHTR1ADRD2HTR1D | |
| Mebufotenin SCHEMBL25344818 | 0.68 | HTR1A (0.68) | HTR6MTNR1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250059-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | SMALL PHARMA LTD (GB) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250059-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | TPH2, TPH1, HTR2C | HTR6 13/4885MTNR1A 151/4885HTR2A 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.