SCHEMBL2550009

SCHEMBL2550009

C#CCCCCC(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.48
BLM P54132 1/20 0.48
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ACE2 Q9BYF1 1/20 0.46
GABRR1 P24046 2/20 0.45
ALDH1A1 P00352 2/20 0.42
USP2 O75604 2/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1585426 1.00 LTA4H (0.48) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL2700090 1.00 LTA4H (0.48) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL25923107 1.00 LTA4H (0.48) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL1246190 0.98 MAPT (0.50) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL1964301 0.98 MAPT (0.50) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL2549430 0.98 MAPT (0.50) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL2542574 0.94 BLM (0.50) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL17583510 0.85 ACE2 (0.44) LTA4HBLMCYP1A2MAPTCYP2D6
SCHEMBL2549304 0.85
Ornithine Aketoglutarate SCHEMBL2323479 0.83 GSR (0.53) LTA4HBLMCYP1A2MAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565474-B2 Discovery, total synthesis, and bioactivity of doscadenamides UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-03 US disclosed
US-20250270567-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS INC (US) 2025-08-28 US disclosed
US-12123004-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2024-10-22 US disclosed
US-12031167-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2024-07-09 US disclosed
US-20230242482-A9 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-08-03 US disclosed
US-20220281816-A1 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES University of Florida Research Foundation, Incorporation (US) 2022-09-08 US disclosed
US-20220259626-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS, INC. 2022-08-18 US disclosed
US-11155843-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2021-10-26 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-20210062234-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS, INC. 2021-03-04 US disclosed
US-20180340198-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS, INC. 2018-11-29 US disclosed
US-9970036-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2018-05-15 US disclosed
US-20160206680-A1 ANTI-TRYPANOSOME COMPOUNDS AND TREATMENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-07-21 US disclosed
US-9321811-B2 Further novel anti-parasitic compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-04-26 US disclosed
US-20160076065-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS, INC. 2016-03-17 US disclosed
US-20140221276-A1 FURTHER NOVEL ANTI-PARASITIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-07 US disclosed
US-8772247-B2 Anti-parasitic compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-08 US disclosed
US-20120108502-A1 NOVEL ANTI-PARASITIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) 2012-05-03 US disclosed
US-20110263815-A1 TRIAZOLE MACROCYCLE SYSTEMS AILERON THERAPEUTICS, INC., A DELAWARE CORPORATION (US) 2011-10-27 US disclosed
WO-2010108164-A2 NOVEL ANTI-PARASITIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281816-A1 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES PDE9A, CGAS, PDE8A LTA4H 1150/4885BLM 1842/4885CYP1A2 2255/4885
US-20110263815-A1 TRIAZOLE MACROCYCLE SYSTEMS FLT3, VIP, NGLY1 LTA4H 3788/4885BLM 2527/4885CYP1A2 3488/4885
US-20220259626-A1 GENERATION OF ACYL AMINO ACIDS FADS1, FADS2, FAR1 LTA4H 635/4885BLM 4842/4885CYP1A2 2540/4885
US-20120108502-A1 NOVEL ANTI-PARASITIC COMPOUNDS NGLY1, PTMS, LRBA LTA4H 35/4885BLM 3585/4885CYP1A2 4265/4885
US-20180340198-A1 GENERATION OF ACYL AMINO ACIDS FADS1, FADS2, COASY LTA4H 700/4885BLM 4814/4885CYP1A2 2715/4885
US-12031167-B2 Generation of acyl amino acids FADS1, FADS2, FAR1 LTA4H 635/4885BLM 4842/4885CYP1A2 2540/4885
US-12565474-B2 Discovery, total synthesis, and bioactivity of doscadenamides TRPC6, NPR1, ADCY6 LTA4H 1597/4885BLM 3568/4885CYP1A2 4264/4885
US-20210062234-A1 GENERATION OF ACYL AMINO ACIDS FADS1, FADS2, COASY LTA4H 700/4885BLM 4814/4885CYP1A2 2715/4885
US-20230242482-A9 DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES PDE9A, CGAS, PDE8A LTA4H 1150/4885BLM 1842/4885CYP1A2 2255/4885
US-20160206680-A1 ANTI-TRYPANOSOME COMPOUNDS AND TREATMENTS PDF, TUFM, TRAP1 LTA4H 179/4885BLM 2198/4885CYP1A2 4748/4885
US-20140221276-A1 FURTHER NOVEL ANTI-PARASITIC COMPOUNDS PTMS, LRBA, PDF LTA4H 25/4885BLM 3369/4885CYP1A2 4317/4885
US-11155843-B2 Generation of acyl amino acids FADS1, FADS2, COASY LTA4H 700/4885BLM 4814/4885CYP1A2 2715/4885
US-20160076065-A1 GENERATION OF ACYL AMINO ACIDS ASNS, DNPEP, BCAT1 LTA4H 1665/4885BLM 4635/4885CYP1A2 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.