Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RGS12 | O14924 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | NOS1 | P29475 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PAH | P00439 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21009255 | 1.00 | HSD17B10 (0.63) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL31026287 | 1.00 | HSD17B10 (0.63) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL29365035 | 1.00 | HSD17B10 (0.63) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL31484058 | 0.84 | CASP7 (0.54) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL29652072 | 0.84 | CASP7 (0.54) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL14714646 | 0.83 | CASP7 (0.62) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL26499714 | 0.81 | MAPT (0.56) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL18257461 | 0.79 | KDM4E (0.43) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL18658771 | 0.79 | KDM4E (0.43) | HSD17B10CASP7KDM4EMAPTBLM | |
| SCHEMBL15325116 | 0.79 | KDM4E (0.43) | HSD17B10CASP7KDM4EMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747627-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | Matterworks Inc (US) | 2026-05-27 | — | — | EP | claimed |
| US-12584924-B2 | Compositions and methods for diagnosing and treating chronic kidney disease | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2026-03-24 | — | — | US | claimed |
| US-20250295658-A1 | ANTIPARASITIC AGENTS AND METHODS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 2025-09-25 | — | — | US | claimed |
| US-12292445-B2 | Methods of selecting subjects for treatment with metabolomic modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-05-06 | — | — | US | claimed |
| CN-119925601-A | Application of tetrahydrobiopterin pathway as target in anti-QDPR deletion type tumor | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2025-05-06 | — | — | CN | claimed |
| CN-119837879-A | Use of aminopterin and its metabolites for treating radiation exposure | PTC医疗MP公司 | 2025-04-18 | — | — | CN | claimed |
| WO-2025040681-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PHENYLKETONURIA | PLUVIA AS (NO) | 2025-02-27 | — | — | WO | claimed |
| WO-2025019764-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | MATTERWORKS INC (US) | 2025-01-23 | — | — | WO | claimed |
| EP-4437319-A1 | METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION | Matterworks Inc (US) | 2024-10-02 | — | — | EP | claimed |
| EP-2456432-B1 | COMPOSITIONS TO REDUCE OXIDATIVE STRESS | UNIV MASSACHUSETTS (US) | 2024-02-28 | — | — | EP | claimed |
| US-20060008869-A1 | Process for production of biopterin compound | ASUBIO PHARAM CO., LTD (JP) | 2006-01-12 | — | — | US | claimed |
| US-20050197341-A1 | Methods for treating pain | GENERAL HOSPITAL CORPORATION, THE | 2005-09-08 | — | — | US | claimed |
| WO-2005048926-A2 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2005-06-02 | — | — | WO | claimed |
| WO-2005049000-A2 | TREATMENT OF PHENYLKETONURIAS WITH BH4 | BIOMARIN PHARMACEUTICAL INC. (US) | 2005-06-02 | — | — | WO | claimed |
| EP-1477165-A2 | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis | Cornell Research Foundation, INC. (US) | 2004-11-17 | — | — | EP | claimed |
| US-20040014167-A1 | Process for producing biopterin | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2004-01-22 | — | — | US | claimed |
| CN-1449442-A | Process for producing biopterins | SUNTORY LTD (JP) | 2003-10-15 | — | — | CN | claimed |
| EP-1314782-A1 | PROCESS FOR PRODUCING BIOPTERINS | SUNTORY LIMITED (JP) | 2003-05-28 | — | — | EP | claimed |
| US-6274581-B1 | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis | CORNELL RESEARCH FOUNDATION, INC. | 2001-08-14 | — | — | US | claimed |
| US-5877176-A | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-03-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12584924-B2 | Compositions and methods for diagnosing and treating chronic kidney disease | GLS, AADAT, FGF23 | HSD17B10 4795/4885CASP7 3918/4885KDM4E 124/4885 |
| US-20050197341-A1 | Methods for treating pain | SPR, QDPR, SHMT1 | HSD17B10 323/4885CASP7 3886/4885KDM4E 2785/4885 |
| US-20250295658-A1 | ANTIPARASITIC AGENTS AND METHODS | DHFR, DHODH, MTHFD1 | HSD17B10 1222/4885CASP7 558/4885KDM4E 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.