SCHEMBL26023964

SCHEMBL26023964

Cc1cc(F)ccc1-c1cc(C(C)(C)C)cc[n+]1C

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.32
GPBAR1 Q8TDU6 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HSP90AB1 P08238 5/20 0.30
KCNH2 Q12809 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25885898 0.89 ALDH1A1 (0.37) ALOX5APALDH1A1MAPTBCHEACHE
SCHEMBL26023978 0.85 KIF11 (0.41) ALOX5APALDH1A1LMNAMAPT
SCHEMBL25884874 0.84 TSHR (0.35) ALDH1A1MAPTBCHEACHE
SCHEMBL25450628 0.80 TSHR (0.36) ALOX5APALDH1A1MAPT
SCHEMBL25884814 0.80 NPC1 (0.39) ALDH1A1BCHEACHE
SCHEMBL26024007 0.79 KIF11 (0.39)
SCHEMBL26023939 0.79 MAPT (0.36) ALDH1A1LMNAMAPTKCNH2
SCHEMBL26326906 0.78 ALDH1A1 (0.36) ALDH1A1MAPTBCHEACHE
SCHEMBL26654352 0.76 PTGS2 (0.32) HSP90AB1
SCHEMBL26023434 0.76 GRIN2B (0.33) GPBAR1HSP90AB1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, SSB ALOX5AP 2711/4885GPBAR1 776/4885ALDH1A1 1192/4885
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR ALOX5AP 3992/4885GPBAR1 2223/4885ALDH1A1 1467/4885
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 ALOX5AP 1616/4885GPBAR1 484/4885ALDH1A1 987/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR ALOX5AP 1088/4885GPBAR1 186/4885ALDH1A1 1046/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 ALOX5AP 2141/4885GPBAR1 435/4885ALDH1A1 545/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR ALOX5AP 3174/4885GPBAR1 533/4885ALDH1A1 1702/4885
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR1H2 ALOX5AP 3286/4885GPBAR1 265/4885ALDH1A1 600/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP ALOX5AP 793/4885GPBAR1 230/4885ALDH1A1 480/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 ALOX5AP 3053/4885GPBAR1 338/4885ALDH1A1 1603/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR ALOX5AP 1716/4885GPBAR1 603/4885ALDH1A1 1681/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 ALOX5AP 3408/4885GPBAR1 727/4885ALDH1A1 569/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 ALOX5AP 2168/4885GPBAR1 227/4885ALDH1A1 728/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 ALOX5AP 4318/4885GPBAR1 3401/4885ALDH1A1 2748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.