SCHEMBL2603585

SCHEMBL2603585

CC1(C)c2ccccc2-c2cc3c(cc21)c1ccccc1n3-c1cc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 4/20 0.38
KMT2A Q03164 6/20 0.34
MEN1 O00255 5/20 0.34
ALDH1A1 P00352 3/20 0.34
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
NTSR1 P30989 1/20 0.32
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
GLA P06280 1/20 0.31
PDE10A Q9Y233 1/20 0.30
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14731161 0.96 MAPT (0.39) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL25966265 0.95 MAPT (0.35) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL21475985 0.95 HTT (0.35) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL25966269 0.95 HTT (0.35) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL25966261 0.92 MAPT (0.33) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL2603605 0.92 MAPT (0.33) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL16919362 0.92 MAPT (0.39) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL25966192 0.91 MAPT (0.35) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL17228360 0.91 HPGD (0.39) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL8735730 0.90 HPGD (0.41) MAPTTSHRMAPK1NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11647669-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-09 US disclosed
US-11647669-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-09 US disclosed
WO-2014166585-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014166584-A1 ORGANIC ELECTROLUMINESCENT DEVICE WITH THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL DUKSAN HIGH METAL CO., LTD. (KR) 2012-01-26 US disclosed
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL DUKSAN HIGH METAL CO., LTD. (KR) 2012-01-26 US disclosed
WO-2011000455-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647669-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 MAPT 1589/4885TSHR 3571/4885MAPK1 1495/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 MAPT 1033/4885TSHR 3493/4885MAPK1 4683/4885
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SLC18A1, CRY1, AADAT MAPT 1483/4885TSHR 2410/4885MAPK1 1210/4885
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, ICMT, NUDC MAPT 1086/4885TSHR 4834/4885MAPK1 1857/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 MAPT 1033/4885TSHR 3493/4885MAPK1 4683/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 MAPT 1037/4885TSHR 3925/4885MAPK1 4348/4885
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL OR10J3, OR51E2, ESR1 MAPT 2358/4885TSHR 3501/4885MAPK1 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.