SCHEMBL2606624

SCHEMBL2606624

C[C@H]1OC(CO)[C@@H](O)C(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.52
LGALS3 P17931 2/20 0.52
LGALS9 O00182 1/20 0.52
LGALS8 O00214 1/20 0.52
PYGB P11216 6/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
FUCA1 P04066 1/20 0.42
MAPT P10636 1/20 0.42
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15299087 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL13542913 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL8244688 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL23816520 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14268507 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL24518019 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL147049 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL13110610 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL21610360 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL9914006 1.00 LGALS1 (0.52) LGALS1LGALS3LGALS9LGALS8PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498724-B1 NUCLEIC ACID COMPLEX KYOWA KIRIN CO LTD (JP) 2023-06-21 EP disclosed
US-20210246157-A1 CAMPTOTHECIN DERIVATIVES AND PREPARATION METHODS AND APPLICATIONS THEREOF Sichuan Fushengyuan Technology Co., Ltd. (CN) 2021-08-12 US disclosed
US-10570104-B2 Metabolically programmed metal chelators and uses thereof UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2020-02-25 US disclosed
US-10408783-B2 Electrochemical methods and compounds for the detection of enzymes GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2019-09-10 US disclosed
WO-2019053700-A2 FUNCTION-BASED PROBES FOR ENVIRONMENTAL MICROBIOME ANALYSIS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE (US) 2019-03-21 WO disclosed
US-10202469-B2 Sugar chain-attached linker, compound containing sugar chain-attached linker and physiologically active substance or salt thereof, and method for producing same GLYTECH, INC. (KP) 2019-02-12 US disclosed
US-10010535-B2 Desferrithiocin analogs and uses thereof UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-07-03 US disclosed
US-20180140581-A1 METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-05-24 US disclosed
US-9879097-B2 Method for producing activated sugar chain derivative and activated sugar chain derivative produced therefrom GLYTECH, INC. (JP) 2018-01-30 US disclosed
EP-2780352-B1 MANNOSYLATED COMPOUNDS USEFUL FOR THE PREVENTION AND THE TREATMENT OF INFECTIOUS DISEASES UNIV STRASBOURG (FR) 2017-11-08 EP disclosed
EP-2762489-A9 GLYCOSYLATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Glytech, Inc. (JP) 2015-02-11 EP disclosed
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GLYTECH, INC. (JP) 2014-11-13 US disclosed
EP-2762489-A1 GLYCOSYLATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Glytech, Inc. (JP) 2014-08-06 EP disclosed
EP-2414372-B1 CHEMICAL SYNTHESIS OF PHOSPHATIDYLINOSITOL MANNOSIDE GLYCANS FROM MYCOBACTERIUM TUBERCULOSIS MAX PLANCK GESELLSCHAFT (DE) 2013-10-23 EP disclosed
US-8536153-B2 Chemical synthesis of phosphatidylinositol mannoside glycans from Mycobacterium tuberculosis MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-09-17 US disclosed
US-8252909-B2 Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases NEW YORK UNIVERSITY (US) 2012-08-28 US disclosed
US-8163705-B2 Glycolipid and use thereof RIKEN (JP) 2012-04-24 US disclosed
WO-2011014715-A2 FLUOROPOLYMER COMPOSITIONS CONTAINING A POLYOL COMPOUND AND METHODS OF MAKING THEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-03 WO disclosed
US-7632941-B2 novel cyclodextrin derivatives, polysubstituted but also monosubstituted, in primary alcohol position by reacting halogenated cyclodextrin with aminoalkanethiol or the salt of aminoalklanethio to form intermediate, then with an isothiocyanate containing biorecognition element such as amino acid, peptide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-12-15 US disclosed
US-20090221516-A1 NOVEL GLYCOLIPID AND USE THEREOF RIKEN (JP) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570104-B2 Metabolically programmed metal chelators and uses thereof FECH, SLC19A1, SLC40A1 LGALS1 3977/4885LGALS3 4453/4885LGALS9 3026/4885
US-10202469-B2 Sugar chain-attached linker, compound containing sugar chain-attached linker and physiologically active substance or salt thereof, and method for producing same SI, ENGASE, DNPEP LGALS1 1064/4885LGALS3 1836/4885LGALS9 830/4885
US-20180140581-A1 METABOLICALLY PROGRAMMED METAL CHELATORS AND USES THEREOF FECH, SLC19A1, SLC40A1 LGALS1 3977/4885LGALS3 4453/4885LGALS9 3026/4885
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GIPR, SSTR4, SSTR5 LGALS1 638/4885LGALS3 671/4885LGALS9 751/4885
US-10408783-B2 Electrochemical methods and compounds for the detection of enzymes EPX, DNASE1, DERA LGALS1 1301/4885LGALS3 1105/4885LGALS9 1567/4885
US-20210246157-A1 CAMPTOTHECIN DERIVATIVES AND PREPARATION METHODS AND APPLICATIONS THEREOF TOP1, TOP2A, TOP2B LGALS1 1344/4885LGALS3 1081/4885LGALS9 1765/4885
US-20090221516-A1 NOVEL GLYCOLIPID AND USE THEREOF IL4, IL2, IL5 LGALS1 146/4885LGALS3 320/4885LGALS9 296/4885
US-10010535-B2 Desferrithiocin analogs and uses thereof FECH, TFRC, FTH1 LGALS1 2325/4885LGALS3 2758/4885LGALS9 2460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.