Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939594 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HTTTSHRMAPT | |
| SCHEMBL28021358 | 0.80 | CALM1 (0.52) | SMN1; SMN2ALDH1A1HTTTSHRMAPT | |
| SCHEMBL6862682 | 0.79 | ALOX15 (0.51) | CRHBPCRHR2SMN1; SMN2DBHMAPT | |
| SCHEMBL31512860 | 0.79 | FOS (0.61) | ALDH1A1MAOBTSHRALOX15ALOX12 | |
| SCHEMBL116330 | 0.79 | FOS (0.61) | ALDH1A1MAOBTSHRALOX15ALOX12 | |
| SCHEMBL2608858 | 0.78 | S1PR1 (0.40) | ALDH1A1HTTTSHRMAPTALOX15 | |
| SCHEMBL13938660 | 0.78 | CRHBP (0.50) | CRHBPCRHR2SMN1; SMN2ALDH1A1KDM1A | |
| SCHEMBL647273 | 0.75 | CA1 (0.44) | SMN1; SMN2HTTTSHRMAPTCA2 | |
| Alcohol SCHEMBL580058 | 0.75 | FOS (0.56) | ALDH1A1MAOBTSHRALOX15ALOX12 | |
| SCHEMBL11282191 | 0.74 | CA2 (0.68) | CRHBPCRHR2SMN1; SMN2ALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | CRHBP 3252/4885CRHR2 3980/4885SMN1; SMN2 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.