Sugi Predict

Sugi Predict / Compounds / SCHEMBL2616641

SCHEMBL2616641

SCHEMBL2616641

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nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.54
▸ ALOX15 P16050 4/20 0.54
▸ TDP1 Q9NUW8 3/20 0.54
▸ TSHR P16473 3/20 0.54
▸ RECQL P46063 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ PTGS1 P23219 2/20 0.52
▸ MAPT P10636 4/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ LMNA P02545 3/20 0.40
▸ NR1I2 O75469 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ CYP3A4 P08684 2/20 0.35
▸ TRPV1 Q8NER1 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ APP P05067 1/20 0.35
▸ SNCA P37840 1/20 0.35
▸ NR2E1 Q9Y466 1/20 0.35
▸ TRPA1 O75762 2/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4289266 1.00 ALDH1A1 (0.54) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL21382128 0.97 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL13903766 0.97 ALDH1A1 (0.58) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL13903777 0.97 ALDH1A1 (0.58) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL13903782 0.90 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL13903775 0.90 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL4124094 0.90 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL4124093 0.90 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1TSHRRECQL
SCHEMBL27921687 0.88 — —
SCHEMBL14542710 0.88 ALDH1A1 (0.45) ALDH1A1ALOX15TDP1TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11523610-B2 Regulating plant growth using a diapocarotenoid KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-12-13 — — US disclosed
US-11523610-B2 Regulating plant growth using a diapocarotenoid KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-12-13 — — US disclosed
US-20210000108-A1 REGULATING PLANT GROWTH USING A DIAPOCAROTENOID UNIV KING ABDULLAH SCI & TECH (SA) 2021-01-07 — — US disclosed
US-20210000108-A1 REGULATING PLANT GROWTH USING A DIAPOCAROTENOID UNIV KING ABDULLAH SCI & TECH (SA) 2021-01-07 — — US disclosed
WO-2019180638-A1 REGULATING PLANT GROWTH USING A DIAPOCAROTENOID KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2019-09-26 — — WO disclosed
US-9950067-B2 Trans carotenoids, their synthesis, formulation and uses Diffusion Pharmaceuticals, LLC (US) 2018-04-24 — — US disclosed
US-20160199490-A1 TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES Diffusion Pharmaceuticals, LLC 2016-07-14 — — US disclosed
US-20160199490-A1 TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES Diffusion Pharmaceuticals, LLC 2016-07-14 — — US disclosed
EP-2540696-A1 Trans carotenoids, their synthesis, formulation and uses Diffusion Pharmaceuticals LLC (US) 2013-01-02 — — EP disclosed
US-8252977-B2 Polynucleotides encoding carotenoid and apocartenoid biosynthetic pathway enzymes in coffee NESTEC S. A. (CH) 2012-08-28 — — US disclosed
US-20090178156-A1 Polynucleotides encoding carotenoid and apocartenoid biosynthetic pathway enzymes in coffee NESTEC S.A. (CH) 2009-07-09 — — US disclosed
US-20090069417-A1 CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS LY CORED LTD. (IL) 2009-03-12 — — US disclosed
US-20090069417-A1 CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS LY CORED LTD. (IL) 2009-03-12 — — US disclosed
EP-1924695-A2 POLYNUCLEOTIDES ENCODING CAROTENOID AND APOCAROTENOID BIOSYNTHETIC PATHWAY Cornell University (US) 2008-05-28 — — EP disclosed
WO-2007028115-A2 POLYNUCLEOTIDES ENCODING CAROTENOID AND APOCAROTENOID BIOSYNTHETIC PATHWAY CORNELL UNIVERSITY (US) 2007-03-08 — — WO disclosed
US-4156100-A INTERMEDIATES FOR OPTICALLY ACTIVE CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1979-05-22 — — US disclosed
US-4095038-A INTERMEDIATES IN THE PRODUCTION OF CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-06-13 — — US disclosed
US-4072715-A CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-02-07 — — US disclosed
US-4026949-A INTERMEDIATES FOR CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1977-05-31 — — US disclosed
US-3988205-A BY FERMENTATIVELY HYDROGENATING AND REDUCING KETOISOPHORONE HOFFMANN-LA ROCHE INC. (US) 1976-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160199490-A1 TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES TTPA, RBP4, TXNRD2 ALDH1A1 3045/4885ALOX15 28/4885TDP1 4025/4885
US-20090069417-A1 CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS DOHH, BBOX1, TXN2 ALDH1A1 27/4885ALOX15 65/4885TDP1 2757/4885
US-20210000108-A1 REGULATING PLANT GROWTH USING A DIAPOCAROTENOID RER1, GRHPR, ERH ALDH1A1 282/4885ALOX15 762/4885TDP1 4677/4885
US-11523610-B2 Regulating plant growth using a diapocarotenoid RER1, GRHPR, ERH ALDH1A1 282/4885ALOX15 762/4885TDP1 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.