Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022187 | 0.78 | MAOA (0.50) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL3174144 | 0.77 | MAOA (0.53) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL29486322 | 0.76 | HTT (0.48) | HTTPTGS1HPGDPTGS2ALDH1A1 | |
| SCHEMBL31545595 | 0.74 | HPGD (0.50) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL24804446 | 0.73 | HTT (0.49) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL17867402 | 0.73 | ACHE (0.60) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL9260013 | 0.73 | CYP19A1 (0.59) | HTTHPGDCYP19A1PTPN1MEN1 | |
| Prenylhydroquinone SCHEMBL7036748 | 0.72 | HTT (0.64) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL8698637 | 0.72 | TYR (0.54) | HTTPTGS1MAOAHPGDPTGS2 | |
| SCHEMBL3564545 | 0.72 | CYP19A1 (0.52) | HTTPTGS1MAOAHPGDCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810078-B1 | DENTIFRICE COMPOSITIONS | PROCTER & GAMBLE (US) | 2024-12-11 | — | — | EP | claimed |
| US-RE49351-E1 | Cytoprotective agent | BIOGEN MA INC. (US) | 2023-01-03 | — | — | US | claimed |
| US-20090270476-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF NEPHRITIS AND MANUFACTURING METHOD THEREOF | JI XING PHARMACEUTICALS HONG KONG LIMITED (HK) | 2009-10-29 | — | — | US | claimed |
| EP-1944027-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF NEPHRITIS AND METHOD FOR PRODUCING SAME | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2008-07-16 | — | — | EP | claimed |
| US-12453718-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) | 2025-10-28 | — | — | US | disclosed |
| US-20250177405-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. | 2025-06-05 | — | — | US | disclosed |
| US-20250099427-A1 | Drug and Method of Treating or Preventing Renal Disease Using Drug | SHOWA MEDICAL UNIVERSITY (JP) | 2025-03-27 | — | — | US | disclosed |
| WO-2025031476-A1 | PREPARATION METHOD FOR SMTP-7 DERIVATIVE AND INTERMEDIATE THEREOF | 上海森辉医药有限公司 | 2025-02-13 | — | — | WO | disclosed |
| EP-3810078-B1 | DENTIFRICE COMPOSITIONS | PROCTER & GAMBLE (US) | 2024-12-11 | — | — | EP | disclosed |
| US-12162935-B2 | Regimens, compositions and methods with capsaicin and TNF-alpha inhibitor | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2024-12-10 | — | — | US | disclosed |
| US-12138244-B2 | Drug and method of treating or preventing renal disease using drug | SHOWA UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| EP-4436567-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | Astrocyte Pharmaceuticals, Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-1944027-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF NEPHRITIS AND METHOD FOR PRODUCING SAME | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2008-07-16 | — | — | EP | disclosed |
| CN-1976697-A | Liver function modifier | AGRICULTURAL IND DAI TLO CO LT (JP) | 2007-06-06 | — | — | CN | disclosed |
| JP-2004224737-A | NEW TRIPRENYLPHENOL COMPOUND | TTC:KK | 2004-08-12 | — | — | JP | disclosed |
| WO-2002038141-A9 | COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20020173549-A1 | Compositions and methods for treatment of mild cognitive impairment | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-21 | — | — | US | disclosed |
| WO-2002038141-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-05-16 | — | — | WO | disclosed |
| JP-2002065288-A | METHOD FOR SELECTIVELY PRODUCING TRIPRENYL PHENOL COMPOUND AND UTILIZATION OF THE SAME COMPOUND AS MEDICINE | HASUMI KEIJI | 2002-03-05 | — | — | JP | disclosed |
| WO-1998056940-A1 | HAIR GROWTH ACTIVATING COMPOSITION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099427-A1 | Drug and Method of Treating or Preventing Renal Disease Using Drug | REN, ATP6V1B1, SLC10A1 | HTT 771/4885PTGS1 97/4885MAOA 542/4885 |
| US-12138244-B2 | Drug and method of treating or preventing renal disease using drug | REN, ATP6V1B1, SLC10A1 | HTT 771/4885PTGS1 97/4885MAOA 542/4885 |
| US-12453718-B2 | Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug | PROC, FABP7, SERPINC1 | HTT 705/4885PTGS1 46/4885MAOA 1132/4885 |
| US-20090270476-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF NEPHRITIS AND MANUFACTURING METHOD THEREOF | THOP1, REN, PTN | HTT 2663/4885PTGS1 66/4885MAOA 1716/4885 |
| US-12162935-B2 | Regimens, compositions and methods with capsaicin and TNF-alpha inhibitor | TNF, TNFRSF1A, TNFRSF9 | HTT 2152/4885PTGS1 333/4885MAOA 3037/4885 |
| US-20250177405-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ADORA2A, ADORA3, ADORA1 | HTT 1961/4885PTGS1 923/4885MAOA 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.