Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.40 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | GABBR2 known ✓ | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 known ✓ | Q9UBS5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.36 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11494507 | 0.95 | GABRA1 (0.40) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| SCHEMBL7179397 | 0.95 | GABRA1 (0.40) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| Lithium Ion SCHEMBL3626995 | 0.95 | GABRA1 (0.40) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| SCHEMBL7177257 | 0.95 | GABRA1 (0.40) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| SCHEMBL6352500 | 0.92 | GABRA1 (0.39) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| SCHEMBL6356731 | 0.90 | GABRA1 (0.37) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| SCHEMBL20597506 | 0.83 | CYP2C19 (0.36) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| Butylated Hydroxytoluene SCHEMBL4826096 | 0.79 | SMN1; SMN2 (0.54) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL17260932 | 0.76 | POLB (0.50) | GABRA1GABRB2POLBALDH1A1ALOX15 | |
| Butylated Hydroxytoluene SCHEMBL23090058 | 0.74 | SMN1; SMN2 (0.54) | POLBALDH1A1ALOX15SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458823-B | Process for preparing unsaturated carboxylic acid salts | 巴斯夫欧洲公司 | 2022-04-19 | — | — | CN | claimed |
| JP-4822651-B2 | — | — | 2011-11-24 | — | — | JP | claimed |
| EP-1324967-A1 | METHOD OF MAKING METAL SALTS OF PHENOLS | GENERAL ELECTRIC COMPANY (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002026681-A1 | METHOD OF MAKING METAL SALTS OF PHENOLS | GENERAL ELECTRIC COMPANY (US) | 2002-04-04 | — | — | WO | claimed |
| CN-106458823-B | Process for preparing unsaturated carboxylic acid salts | 巴斯夫欧洲公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-106458824-B | Method for preparing unsaturated carboxylic acid salt using aryl oxide | 巴斯夫欧洲公司 | 2020-10-16 | — | — | CN | disclosed |
| US-6930106-B2 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY (US) | 2005-08-16 | — | — | US | disclosed |
| EP-1525186-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1525183-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1309600-B1 | PROCESS FOR THE PREPARATION OF HINDERED PHOSPHITES | CROMPTON CORP (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6773624-B2 | REACTING GLYCOL SUCH AS PENTAERYTHRITOL WITH PHOSPHORUS TRIHALIDE TO PRODUCE HALO PHOSPHITE ESTER OF GLYCOL, REACTING PRODUCT WITH A PHENOL, REACTING SECOND PRODUCTS COMPRISING ORGANIC PHOSPHITE AND HALO PHOSPHITE WITH METAL PHENOLATE | CROMPTON CORPORATION | 2004-08-10 | — | — | US | disclosed |
| US-20040142989-A1 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| EP-1309600-A1 | PROCESS FOR THE PREPARATION OF HINDERED PHOSPHITES | GENERAL ELECTRIC COMPANY (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030083530-A1 | Metal salts of hindered aromatic phenols | GENERAL ELECTRIC CO. | 2003-05-01 | — | — | US | disclosed |
| US-6504065-B1 | Reacting phenolic alcohols with alcoholates to obtain phenolates used as stabilizer agents in the reactions of hindered phenol and phosphite esters; kinetics | GENERAL ELECTRIC COMPANY | 2003-01-07 | — | — | US | disclosed |
| US-20020193620-A1 | Process for the preparation of hindered phosphites | GENERAL ELECTRIC CO. | 2002-12-19 | — | — | US | disclosed |
| US-6426429-B1 | REACTING A GLYCOL WITH A PHOSPHORUS TRI-HALIDE, REACTING THE HALO PHOSPHITE ESTER PRODUCT WITH A PHENOL, AND FURTHER REACTING ITS PRODUCT WITH A METAL PHENOLATE | GENERAL ELECTRIC COMPANY | 2002-07-30 | — | — | US | disclosed |
| WO-2002026681-A1 | METHOD OF MAKING METAL SALTS OF PHENOLS | GENERAL ELECTRIC COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002014335-A1 | PROCESS FOR THE PREPARATION OF HINDERED PHOSPHITES | GENERAL ELECTRIC COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
| US-6235938-B1 | ARYLATION IN THE PRESENCE OF A BASE AND TRANSITION METAL CATALYSTS TO FORM N-ARYLAMINE AND GROUP 8 METAL | YALE UNIVERSITY | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083530-A1 | Metal salts of hindered aromatic phenols | EP300, BET1, TYR | GABRA1 3513/4885GABRB2 3905/4885CA2 41/4885 |
| US-20020193620-A1 | Process for the preparation of hindered phosphites | PTEN, PTPRS, INPPL1 | GABRA1 2468/4885GABRB2 2777/4885CA2 2060/4885 |
| US-20040142989-A1 | Inhibitors of HCV NS5B polymerase | POLRMT, POLR1E, CTDSP1 | GABRA1 4448/4885GABRB2 4589/4885CA2 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.