Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465704 | 0.80 | CACNA1H (0.51) | CACNA1HAR | |
| SCHEMBL26464503 | 0.79 | KCNT1 (0.49) | CACNA1HPOLBPKMLMNAMEN1 | |
| SCHEMBL26465811 | 0.76 | ALDH1A1 (0.49) | CACNA1HPOLBPKMLMNAMEN1 | |
| SCHEMBL26465689 | 0.75 | CACNA1H (0.54) | CACNA1HLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL26465573 | 0.75 | CACNA1H (0.72) | CACNA1HLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26464490 | 0.75 | CACNA1H (0.54) | CACNA1HCXCR6 | |
| SCHEMBL26465710 | 0.75 | HTT (0.50) | CACNA1HPOLBLMNAMEN1KMT2A | |
| SCHEMBL26465699 | 0.74 | HPGD (0.55) | CACNA1HLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26465812 | 0.73 | CACNA1H (0.47) | CACNA1HPOLBLMNAMEN1KMT2A | |
| SCHEMBL26465838 | 0.72 | CACNA1H (0.55) | CACNA1HALDH1A1CXCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |