SCHEMBL26555703

SCHEMBL26555703

Cc1ccc(-c2ccc(C)c(-c3ccc(C#N)cc3)c2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 6/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ CYP2A6 P11509 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ CYP11B1 P15538 2/20 0.42
▸ CTSK P43235 1/20 0.41
▸ KIF11 P52732 2/20 0.40
▸ MMP3 P08254 1/20 0.39
▸ EGLN2 Q96KS0 2/20 0.39
▸ KDM1A O60341 1/20 0.38
▸ ABL1 P00519 1/20 0.38
▸ MAPK14 Q16539 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10304732 0.88 KIF11 (0.50) CYP11B2ALDH1A1CYP2A6TP53CTSK
SCHEMBL26555707 0.87 CTSK (0.40) CYP11B2TP53CYP11B1CTSKABL1
SCHEMBL10110951 0.83 ALDH1A1 (0.56) CYP11B2ALDH1A1CYP2A6CYP11B1KIF11
SCHEMBL16945958 0.83 KIF11 (0.47) CYP11B2ALDH1A1CYP2A6TP53CYP11B1
SCHEMBL10094654 0.80 PTGS1 (0.49) CYP11B2ALDH1A1CYP2A6TP53CYP11B1
SCHEMBL26532556 0.79 CYP11B2 (0.43) CYP11B2CYP11B1CTSKEGLN2KDM1A
SCHEMBL25767772 0.78 CYP11B1 (0.45) CYP11B2ALDH1A1CYP2A6TP53CYP11B1
SCHEMBL29306055 0.76 ALDH1A1 (0.57) CYP11B2ALDH1A1CYP2A6KIF11MMP3
SCHEMBL29788076 0.76 PTGDR2 (0.49) CYP11B2ALDH1A1CYP11B1MAPK14GAA
SCHEMBL15856481 0.76 PTGDR2 (0.49) CYP11B2ALDH1A1CYP11B1MAPK14GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 CYP11B2 2500/4885ALDH1A1 987/4885CYP2A6 3671/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 CYP11B2 2154/4885ALDH1A1 784/4885CYP2A6 4079/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR CYP11B2 2785/4885ALDH1A1 1702/4885CYP2A6 3909/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR CYP11B2 2449/4885ALDH1A1 1681/4885CYP2A6 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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