SCHEMBL26555707

SCHEMBL26555707

Cc1ccc(-c2ccc(C)c(-c3cc(C#N)cc(C#N)c3)c2)cc1C

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 1/20 0.40
▸ PGR P06401 3/20 0.38
▸ AR P10275 2/20 0.38
▸ CYP11B1 P15538 1/20 0.38
▸ CYP11B2 P19099 1/20 0.38
▸ TP53 P04637 1/20 0.36
▸ MAPK14 Q16539 3/20 0.36
▸ ABL1 P00519 1/20 0.35
▸ MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26555703 0.87 CYP11B2 (0.44) CTSKCYP11B1CYP11B2TP53MAPK14
SCHEMBL26652440 0.85 RXRA (0.46) CTSKPGRARCYP11B1CYP11B2
SCHEMBL26532559 0.80 GRM5 (0.42) CTSKCYP11B1CYP11B2MAPK14ABL1
SCHEMBL10304732 0.79 KIF11 (0.50) CTSKPGRCYP11B2TP53
SCHEMBL18406713 0.76 AR (0.49) ARCYP11B1CYP11B2
Water SCHEMBL9222873 0.73 ALDH1A1 (0.52) CTSKTP53MCL1
SCHEMBL18204279 0.73 MEN1 (0.39) PGRAR
SCHEMBL25767772 0.73 CYP11B1 (0.45) CYP11B1CYP11B2TP53
SCHEMBL17546156 0.71 AR (0.40) PGRARCYP11B1CYP11B2MAPK14
SCHEMBL16945958 0.71 KIF11 (0.47) CYP11B1CYP11B2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 CTSK 2180/4885PGR 1289/4885AR 829/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 CTSK 3244/4885PGR 2459/4885AR 1225/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR CTSK 3486/4885PGR 1443/4885AR 524/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR CTSK 1921/4885PGR 2026/4885AR 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback