SCHEMBL2656864

SCHEMBL2656864

Cc1nc(F)ccc1B(O)O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29698271 1.00 CA2 (0.31) CA2LPLLIPG
SCHEMBL426850 0.79
Water SCHEMBL1669028 0.77
Water SCHEMBL29954949 0.77
SCHEMBL30788696 0.76 CCR1 (0.40) CA2LPLLIPG
SCHEMBL489376 0.76 CCR1 (0.40) CA2LPLLIPG
SCHEMBL14929718 0.76
SCHEMBL13260555 0.76 ENPP2 (0.30)
SCHEMBL29951491 0.74 CA2 (0.32) CA2LPLLIPG
SCHEMBL29954944 0.74 NPC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
EP-4634190-A1 NOVEL COMPOUNDS FOR DIAGNOSIS AC Immune SA (CH) 2025-10-22 EP disclosed
US-12168655-B2 Apelin receptor agonists and methods of use BRISTOL-MYERS SQUIBB COMPANY (US) 2024-12-17 US disclosed
WO-2024232597-A1 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF 엘젠테라퓨틱스 주식회사 2024-11-14 WO disclosed
US-20240336574-A1 METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE LATIGO BIOTHERAPEUTICS, INC. 2024-10-10 US disclosed
CN-118359538-A Isoquinoline compound, preparation method, pharmaceutical composition and application thereof 上海赛默罗生物科技有限公司 2024-07-19 CN disclosed
WO-2024126840-A1 NOVEL COMPOUNDS FOR DIAGNOSIS AC IMMUNE SA (CH) 2024-06-20 WO disclosed
EP-4304585-A2 METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE Latigo Biotherapeutics, Inc. (US) 2024-01-17 EP disclosed
CN-113166151-B Substituted xanthine derivatives 勃林格殷格翰国际有限公司 2023-12-01 CN disclosed
US-20230373978-A1 HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-11-23 US disclosed
US-7524870-B2 Biaryloxymethylarenecarboxylic acids as glycogen synthase activators HOFFMANN-LA ROCHE INC. (US) 2009-04-28 US disclosed
EP-2007750-A1 AZABICYCLO [3. 1. 0] HEXYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2008-12-31 EP disclosed
US-20080318943-A1 Compounds and Uses Thereof - 848 ASTRAZENECA AB (SE) 2008-12-25 US disclosed
WO-2008155572-A2 FUSED QUINOLINE DERIVATIVES USEFUL AS GABA MODULATORS ASTRAZENECA AB (SE) 2008-12-24 WO disclosed
US-20070249642-A1 Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione GLAXO GROUP LIMITED (GB) 2007-10-25 US disclosed
WO-2007113232-A1 AZABICYCLO [3. 1. 0] HEXYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2007-10-11 WO disclosed
US-20070054916-A1 Aryl nitrogen-containing bicyclic compounds and methods of use AMGEN INC. 2007-03-08 US disclosed
US-20070054916-A1 Aryl nitrogen-containing bicyclic compounds and methods of use AMGEN INC. 2007-03-08 US disclosed
US-20070054916-A1 Aryl nitrogen-containing bicyclic compounds and methods of use AMGEN INC. 2007-03-08 US disclosed
US-20060122256-A1 Biaryloxymethylarenecarboxylic acids as glycogen synthase activators GILLESPIE PAUL 2006-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122256-A1 Biaryloxymethylarenecarboxylic acids as glycogen synthase activators GYS2, GYS1, GSK3A CA2 574/4885LPL 616/4885LIPG 896/4885
US-20080318943-A1 Compounds and Uses Thereof - 848 COMT, BACE1, BDNF CA2 4588/4885LPL 3153/4885LIPG 4869/4885
US-12168655-B2 Apelin receptor agonists and methods of use APLNR, AP2B1, AP3B1 CA2 1391/4885LPL 1957/4885LIPG 2235/4885
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, C1S, C9 CA2 4475/4885LPL 517/4885LIPG 248/4885
US-20070249642-A1 Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione AZI2, NT5C3B, CYP1B1 CA2 3616/4885LPL 4821/4885LIPG 4641/4885
US-20070054916-A1 Aryl nitrogen-containing bicyclic compounds and methods of use MAP3K1, MAP3K5, MAP3K2 CA2 2730/4885LPL 3851/4885LIPG 2157/4885
US-20230373978-A1 HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES F3, ABL1, CFTR CA2 4323/4885LPL 3950/4885LIPG 4311/4885
US-20240336574-A1 METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE P2RX5, HRH4, TRPV1 CA2 1931/4885LPL 4838/4885LIPG 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.