Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20130358 | 0.84 | TSHR (0.53) | PLK1TSHRNPC1RAB9AHTT | |
| SCHEMBL10205950 | 0.82 | PLK1 (0.54) | PLK1TSHRNPC1RAB9AHTT | |
| SCHEMBL20099353 | 0.78 | PLK1 (0.54) | PLK1TSHRNPC1RAB9AHTT | |
| SCHEMBL9786552 | 0.78 | PTGS2 (0.56) | PLK1TSHRPTGS2CHRNA7 | |
| SCHEMBL5857932 | 0.77 | ALDH1A1 (0.58) | TSHRNPC1RAB9AHTTCYP2C9 | |
| SCHEMBL2449412 | 0.77 | PLK1 (0.73) | PLK1TSHRHTTPTGS2ALDH1A1 | |
| SCHEMBL27672569 | 0.77 | PTGS2 (0.51) | PLK1TSHRPTGS2 | |
| SCHEMBL10369631 | 0.75 | PLK1 (0.71) | PLK1TSHRPTGS2ALDH1A1KMT2A | |
| SCHEMBL14280209 | 0.74 | HTT (0.55) | PLK1TSHRNPC1RAB9AHTT | |
| SCHEMBL6457336 | 0.74 | PLK1 (0.69) | PLK1TSHRPTGS2ALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10454042-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2019-10-22 | — | — | US | disclosed |
| US-9287515-B2 | Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices | UDC Ireland (IE) | 2016-03-15 | — | — | US | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-20120153272-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153272-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES, INC. (KR) | 2012-04-19 | — | — | US | disclosed |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES, INC. (KR) | 2012-04-19 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1995240-B1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-7993760-B2 | Compound for use in organic electroluminescent device and organic electroluminescent device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7993760-B2 | Compound for use in organic electroluminescent device and organic electroluminescent device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090302742-A1 | Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-1995240-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1956022-A1 | COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT | Nippon Steel Chemical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | P2RY10, P2RY12, P2RY11 | PLK1 1611/4885TSHR 1541/4885NPC1 2947/4885 |
| US-20090302742-A1 | Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device | LAGE3, ICMT, PPOX | PLK1 664/4885TSHR 4025/4885NPC1 4722/4885 |
| US-20120091445-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE | OR51E2, AOX1, OR10J3 | PLK1 3714/4885TSHR 3336/4885NPC1 1944/4885 |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | P2RY12, P2RY11, P2RY10 | PLK1 1806/4885TSHR 1363/4885NPC1 3482/4885 |
| US-10454042-B2 | Organic electroluminescence device | EML4, ELOC, ORC3 | PLK1 968/4885TSHR 4463/4885NPC1 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.