Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 17/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 16/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066797 | 1.00 | THRB (0.43) | THRBCA2CA1MMP1MMP2 | |
| Potassium Ion SCHEMBL27498497 | 0.96 | THRB (0.43) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL27677621 | 0.80 | THRB (0.46) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL28064218 | 0.78 | THRB (0.45) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL27712919 | 0.78 | THRB (0.45) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL27865172 | 0.78 | CA2 (0.38) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL22322503 | 0.77 | THRB (0.43) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL7174850 | 0.76 | CA1 (0.45) | THRBCA2CA1F2PRSS1 | |
| SCHEMBL16505929 | 0.76 | THRB (0.42) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL28232140 | 0.74 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250369-B | Aqueous composite paint containing amphiphilic fluorine-containing acrylate blocking copolymer and preparation thereof | GUANGZHOU INST OF CHEMISTRY | 2010-12-15 | — | — | CN | claimed |
| CN-101250369-A | Aqueous composite paint containing amphiphilic fluorine-containing acrylate blocking copolymer and preparation thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2008-08-27 | — | — | CN | claimed |
| CN-1861648-A | Mfg. process and tech. of fluorine carbon emulsion for paint | HONGFENG FLUORINE SILICON SCI (CN) | 2006-11-15 | — | — | CN | claimed |
| CN-101250369-B | Aqueous composite paint containing amphiphilic fluorine-containing acrylate blocking copolymer and preparation thereof | GUANGZHOU INST OF CHEMISTRY | 2010-12-15 | — | — | CN | disclosed |
| CN-101250369-A | Aqueous composite paint containing amphiphilic fluorine-containing acrylate blocking copolymer and preparation thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-1861648-A | Mfg. process and tech. of fluorine carbon emulsion for paint | HONGFENG FLUORINE SILICON SCI (CN) | 2006-11-15 | — | — | CN | disclosed |