Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 11/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713245 | 0.86 | RAB9A (0.53) | SFRP1VNN1POLBKMT2ALMNA | |
| SCHEMBL4617665 | 0.79 | KDM1A (0.52) | SFRP1VNN1GPR119HPGDSADRA1A | |
| SCHEMBL4616149 | 0.79 | NAMPT (0.54) | SFRP1VNN1GPR119HPGDSKMT2A | |
| SCHEMBL28753553 | 0.78 | MGLL (0.52) | POLBKMT2ALMNA | |
| SCHEMBL27733598 | 0.78 | LMNA (0.57) | POLBKMT2ALMNAL3MBTL3 | |
| SCHEMBL27713229 | 0.77 | GAA (0.55) | POLBKMT2ALMNAHPGD | |
| SCHEMBL22031741 | 0.76 | KMT2A (0.51) | POLBKMT2ALMNAL3MBTL3 | |
| SCHEMBL1808354 | 0.75 | ALDH1A1 (0.51) | KMT2A | |
| SCHEMBL28238844 | 0.73 | KMT2A (0.46) | POLBKMT2ALMNAHPGDL3MBTL3 | |
| SCHEMBL27713264 | 0.73 | GPR119 (0.45) | SFRP1VNN1GPR119HPGDSADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |