Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770717 | 0.80 | KDM4E (0.35) | HSD17B10ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL27995323 | 0.80 | TERT (0.34) | TERTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL25178380 | 0.78 | MAPT (0.48) | TERTALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL27712033 | 0.76 | MAPT (0.38) | TERTALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL28774862 | 0.75 | LMNA (0.39) | HSD17B10SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28897005 | 0.73 | HSD17B10 (0.41) | TERTHSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27447779 | 0.73 | CD274 (0.46) | TERTHSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27692022 | 0.72 | PRKCZ (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28436430 | 0.72 | MAPT (0.40) | TERTALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL28158503 | 0.70 | TERT (0.35) | TERTALDH1A1SMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243050-B | Pyrazolone derivatives | HOFFMANN LA ROCHE | 2012-07-04 | — | — | CN | disclosed |
| CN-101243050-A | Pyrazolone derivatives | HOFFMANN LA ROCHE (CH) | 2008-08-13 | — | — | CN | disclosed |