Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25178380 | 0.81 | MAPT (0.48) | TERTSMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL28207258 | 0.81 | TSHR (0.36) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL27369841 | 0.79 | ALDH1A1 (0.43) | TERTSMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL27712033 | 0.79 | MAPT (0.38) | TERTNPSR1SMN1; SMN2MAPTHTT | |
| SCHEMBL29018666 | 0.76 | NR3C2 (0.41) | SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL28897005 | 0.76 | HSD17B10 (0.41) | TERTSMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL27692022 | 0.75 | PRKCZ (0.45) | SMN1; SMN2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL27995307 | 0.74 | TERT (0.36) | TERTNPSR1SMN1; SMN2KMT2A | |
| SCHEMBL27800063 | 0.73 | ALDH1A1 (0.30) | TERTSMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL27447779 | 0.70 | CD274 (0.46) | TERTNPSR1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021928-A | New intermediate of eltrombopag olamine and its preparation method and application | 常州制药厂有限公司 | 2017-08-08 | — | — | CN | disclosed |