Sugi Predict

Sugi Predict / Compounds / SCHEMBL2773644

SCHEMBL2773644

SCHEMBL2773644

CCCCc1ccc(OB(Oc2ccc(CCCC)cc2)Oc2ccc(CCCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 2/20 0.52
▸ CA1 P00915 1/20 0.52
▸ LPL P06858 4/20 0.46
▸ LIPG Q9Y5X9 4/20 0.46
▸ ALDH1A1 P00352 4/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ HPGD P15428 2/20 0.46
▸ THRB P10828 2/20 0.45
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ TRPV1 Q8NER1 1/20 0.44
▸ MGLL Q99685 1/20 0.44
▸ LMNA P02545 3/20 0.44
▸ ESR1 P03372 2/20 0.44
▸ ADRA2A P08913 2/20 0.44
▸ ADORA3 P0DMS8 2/20 0.44
▸ TACR2 P21452 2/20 0.44
▸ SLC6A2 P23975 2/20 0.44
▸ SLC6A4 P31645 2/20 0.44
▸ SLC6A3 Q01959 2/20 0.44
▸ CYP3A4 P08684 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1487719 0.94 LPL (0.53) CA2CA1LPLLIPGALDH1A1
SCHEMBL2769520 0.92 ESR1 (0.55) LPLLIPGALDH1A1HSD17B10THRB
SCHEMBL2770828 0.92 ESR1 (0.55) LPLLIPGALDH1A1HSD17B10THRB
SCHEMBL718156 0.92 ESR1 (0.55) LPLLIPGALDH1A1HSD17B10THRB
SCHEMBL7929576 0.87 LPL (0.48) CA2LPLLIPGALDH1A1THRB
SCHEMBL2773646 0.84 CA1 (0.58) CA2CA1LPLLIPGALDH1A1
SCHEMBL6399912 0.84 CA1 (0.58) CA2CA1LPLLIPGALDH1A1
SCHEMBL7929631 0.81 TDP1 (0.40) ALDH1A1HPGDTHRBSMN1; SMN2LMNA
SCHEMBL145761 0.80 LTA4H (0.52) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL83869 0.79 CA2 (0.65) CA2CA1LPLLIPGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-02 — — US disclosed
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-04-18 — — US disclosed
EP-4308571-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME 3M Innovative Properties Company (US) 2024-01-24 — — EP disclosed
EP-1454921-B1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE TOKUYAMA CORP (JP) 2021-07-28 — — EP disclosed
EP-2778216-A1 ADDITIVE FOR LUBRICATING OILS AND LUBRICATING OIL COMPOSITION JX Nippon Oil & Energy Corporation (JP) 2014-09-17 — — EP disclosed
US-20140100147-A1 LUBRICANT ADDITIVE AND LUBRICANT OIL COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-04-10 — — US disclosed
US-7812172-B2 Charge transport materials; for organic electronic devices such as organic photoreceptors, organic electroluminescence devices, organic transistors, and organic optical memories FUJI XEROX CO., LTD. (JP) 2010-10-12 — — US disclosed
US-20100137611-A1 THIAZOLOTHIAZOLE DERIVATIVE FUJI XEROX CO., LTD. (JP) 2010-06-03 — — US disclosed
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device KYUSHU UNIVERSITY (JP) 2009-07-16 — — US disclosed
US-20050009946-A1 Radical polymerization catalyst and adhesive kit for dental use TOKUYAMA CORPORATION (JP) 2005-01-13 — — US disclosed
EP-1454921-A1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE Tokuyama Corporation (JP) 2004-09-08 — — EP disclosed
US-4281173-A Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1981-07-28 — — US disclosed
US-4195184-A Preparation of unsaturated monoesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1980-03-25 — — US disclosed
US-4189599-A Preparation of dimethyl adipate by the hydrogenation of dimethyl hex-3-endioate ATLANTIC RICHFIELD COMPANY (US) 1980-02-19 — — US disclosed
US-4171450-A Preparation of unsaturated diesters by catalytic oxidative carbonylation of diolefins ATLANTIC RICHFIELD COMPANY (US) 1979-10-16 — — US disclosed
US-4041068-A AS CATALYST A PALLADIUM, PLATINUM OR RHODIUM SALT WITH AN AMINE AND AN ALCOHOL ATLANTIC RICHFIELD COMPANY (US) 1977-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device PPOX, JUP, TARDBP CA2 4583/4885CA1 3980/4885LPL 1946/4885
US-20100137611-A1 THIAZOLOTHIAZOLE DERIVATIVE BCAT1, ABAT, BCAT2 CA2 1903/4885CA1 3516/4885LPL 3573/4885
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same CTRB2, CBR1, CCNB3 CA2 502/4885CA1 670/4885LPL 4182/4885
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME CTRB2, CBR1, CCNB3 CA2 428/4885CA1 558/4885LPL 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.