SCHEMBL2773933

SCHEMBL2773933

O=C(Cl)CCc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.56
ESR2 Q92731 2/20 0.56
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 3/20 0.53
CYP19A1 P11511 2/20 0.53
CYP2C19 P33261 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 2/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
SLC16A3 O15427 1/20 0.53
LMNA P02545 1/20 0.53
TTR P02766 1/20 0.53
TP53 P04637 1/20 0.53
CYP1A2 P05177 1/20 0.53
POLB P06746 1/20 0.53
CYP3A4 P08684 1/20 0.53
GAA P10253 1/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135914 0.91 FFAR1 (0.50) ESR1KDM4EALDH1A1KMT2ACYP19A1
SCHEMBL19612707 0.84 ACHE (0.58) ESR1ESR2KDM4EALDH1A1LMNA
SCHEMBL9440306 0.82 CA1 (0.48) ALDH1A1TDP1HDAC2HDAC8CA2
SCHEMBL1154480 0.82 PLAAT3 (0.53) KDM4EALDH1A1KMT2ACYP2C19MEN1
SCHEMBL8108885 0.81 ESR1 (0.62) ESR1ESR2KDM4EALDH1A1KMT2A
SCHEMBL1446802 0.80 FFAR1 (0.55) ALDH1A1TDP1LMNACYP1A2MAPT
SCHEMBL30799017 0.80 ALDH1A1 (0.48) ALDH1A1HDAC2HDAC8LMNATSHR
SCHEMBL27505250 0.80 TPSAB1 (0.47) KDM4ECA2
SCHEMBL594085 0.80 FFAR1 (0.50) KMT2AMEN1POLBTAAR1
SCHEMBL1154606 0.80 FFAR1 (0.55) LMNAGAASLC5A1HPGDSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117902994-B Preparation method of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 中山海泓药业有限公司 2026-05-19 CN claimed
CN-118290291-A Synthesis method of dihydro oat alkaloid D 微著生物科技(东营)有限责任公司 2024-07-05 CN claimed
CN-117902994-A Preparation method of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 中山海泓药业有限公司 2024-04-19 CN claimed
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN claimed
CN-117902994-B Preparation method of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 中山海泓药业有限公司 2026-05-19 CN disclosed
CN-118290291-A Synthesis method of dihydro oat alkaloid D 微著生物科技(东营)有限责任公司 2024-07-05 CN disclosed
CN-117902994-A Preparation method of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 中山海泓药业有限公司 2024-04-19 CN disclosed
CN-117902994-A Preparation method of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 中山海泓药业有限公司 2024-04-19 CN disclosed
CN-117800866-A Synthesis method and application of 2- (3- (4-hydroxyphenyl) propionylamino) benzoic acid 信阳师范学院 2024-04-02 CN disclosed
CN-112939803-B Preparation process of dihydro oat alkaloid D 郑州轻工业大学 2023-07-18 CN disclosed
CN-114478296-A Preparation method of dihydrooat alkaloid 河南旭瑞新材料科技有限公司 2022-05-13 CN disclosed
CN-109553550-B Method for synthesizing dihydrooat alkaloid 上海克琴科技有限公司 2022-02-22 CN disclosed
US-20100249078-A1 TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPS RESEARCH INSTITUTE (US) 2010-09-30 US disclosed
US-7727434-B2 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY (US) 2010-06-01 US disclosed
EP-2152082-A1 TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE The Scripps Research Institute (US) 2010-02-17 EP disclosed
WO-2008147553-A1 TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2008-12-04 WO disclosed
US-20070112009-A1 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them LABORATOIRE THERAMEX (MC) 2007-05-17 US disclosed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US disclosed
EP-1694650-A1 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LABORATOIRE THERAMEX (MC) 2006-08-30 EP disclosed
WO-2005058842-A1 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LABORATOIRE THERAMEX (MC) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249078-A1 TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, APEH ESR1 3946/4885ESR2 2370/4885KDM4E 1417/4885
US-20070112009-A1 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ESR1 2656/4885ESR2 3407/4885KDM4E 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.