SCHEMBL277492

SCHEMBL277492

Ic1ccccc1-c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.56
LMNA P02545 3/20 0.56
CCR1 P32246 3/20 0.56
CCR5 P51681 3/20 0.56
CCR8 P51685 3/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
METAP1 P53582 1/20 0.56
BLM P54132 1/20 0.56
HIF1A Q16665 1/20 0.56
DOHH Q9BU89 1/20 0.56
P4HTM Q9NXG6 1/20 0.56
DCTPP1 Q9H773 1/20 0.49
NPC1 O15118 5/20 0.48
TP53 P04637 4/20 0.48
RAB9A P51151 4/20 0.48
ALOX15 P16050 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL858806 0.83 KDM4E (0.72) KDM4ELMNACCR1CCR5CCR8
SCHEMBL24297979 0.82 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL12853975 0.80 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29723140 0.80 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL12853986 0.80 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL22881677 0.80 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL19961428 0.79 CYP2A6 (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16712979 0.79 CYP2A6 (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5322720 0.79 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL12887898 0.78 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113336786-B Diastereoselective polysubstituted naphthenic compound and preparation method thereof 南京工业大学 2022-10-18 CN claimed
CN-113336786-A Diastereoselective polysubstituted naphthenic compound and preparation method thereof 南京工业大学 2021-09-03 CN claimed
US-10487099-B2 Synthesis of hypervalent iodine reagents with dioxygen THE TEXAS A&M UNIVERSITY SYSTEM (US) 2019-11-26 US claimed
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-20230380199-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
EP-3131879-B1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2023-09-13 EP disclosed
CN-113336786-B Diastereoselective polysubstituted naphthenic compound and preparation method thereof 南京工业大学 2022-10-18 CN disclosed
US-20220098223-A1 HEXACOORDINATED ORGANOANTIMONY COMPLEX AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME TOKYO METROPOLITAN PUBLIC UNIVERSITY CORPORATION (JP) 2022-03-31 US disclosed
CN-114249770-A 6-coordinated organoantimony compound and organic EL element using 6-coordinated organoantimony compound 东京都公立大学法人 2022-03-29 CN disclosed
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-11-11 US disclosed
US-8134005-B2 Preparation and use of magnesium amides Ludwig-Maximilians-Universitat München (DE) 2012-03-13 US disclosed
EP-2360161-A1 Preparation and use of magnesium amides Ludwig-Maximilians-Universität München (DE) 2011-08-24 EP disclosed
EP-1981893-B1 PREPARATION AND USE OF MAGNESIUM AMIDES UNIV MUENCHEN L MAXIMILIANS (DE) 2011-06-08 EP disclosed
US-20100144516-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2010-06-10 US disclosed
US-20100144516-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2010-06-10 US disclosed
US-20090176988-A1 Preparation and Use of Magnesium Amides LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) 2009-07-09 US disclosed
US-20090176988-A1 Preparation and Use of Magnesium Amides LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) 2009-07-09 US disclosed
WO-2008087057-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2008-07-24 WO disclosed
WO-2007123910-A2 COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO BRANDEIS UNIVERSITY (US) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME BLVRB, CDYL, CRY1 KDM4E 628/4885LMNA 1432/4885CCR1 4580/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 KDM4E 628/4885LMNA 1432/4885CCR1 4580/4885
US-20220098223-A1 HEXACOORDINATED ORGANOANTIMONY COMPLEX AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME OCIAD2, OCIAD1, OSTC KDM4E 3425/4885LMNA 4189/4885CCR1 3236/4885
US-20090176988-A1 Preparation and Use of Magnesium Amides MLX, GLRX3, SFXN3 KDM4E 3049/4885LMNA 1720/4885CCR1 988/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 KDM4E 4161/4885LMNA 338/4885CCR1 1427/4885
US-10487099-B2 Synthesis of hypervalent iodine reagents with dioxygen TPO, HAO2, OGFOD1 KDM4E 2775/4885LMNA 4840/4885CCR1 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.