Sugi Predict

Sugi Predict / Compounds / SCHEMBL277960

SCHEMBL277960

SCHEMBL277960

CCCC(=O)C(C)(C)CC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.43
▸ CES1 P23141 7/20 0.43
▸ CES2 O00748 4/20 0.43
▸ HDAC3 O15379 4/20 0.41
▸ HDAC1 Q13547 4/20 0.41
▸ HDAC2 Q92769 4/20 0.41
▸ HDAC8 Q9BY41 4/20 0.41
▸ FFAR3 O14843 3/20 0.41
▸ TSHR P16473 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.36
▸ FAAH O00519 8/20 0.36
▸ CTSD P07339 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13892337 0.88 ALDH1A1 (0.35) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL464492 0.84 FAAH (0.48) ALDH1A1CES1CES2FAAHMEN1
SCHEMBL18906116 0.83 FAAH (0.41) ALDH1A1CES1CES2TSHRFAAH
SCHEMBL2607813 0.82 FAAH (0.58) ALDH1A1CES1CES2TSHRFAAH
SCHEMBL28946097 0.81 CES1 (0.41) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL19845108 0.81 CYP4F2 (0.32) ALDH1A1FAAH
SCHEMBL23386452 0.80 FAAH (0.59) ALDH1A1CES1CES2TSHRFAAH
SCHEMBL21257214 0.80 FAAH (0.59) ALDH1A1CES1CES2TSHRFAAH
SCHEMBL21422317 0.80 FAAH (0.59) ALDH1A1CES1CES2TSHRFAAH
SCHEMBL22525181 0.80 FAAH (0.59) ALDH1A1CES1CES2TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7704929-B2 Diaromatic amine derivatives as antioxidants CHEMTURA CORPORATION (US) 2010-04-27 — — US claimed
US-20070155633-A1 Diaromatic amine derivatives as antioxidants LANXESS SOLUTIONS US INC. 2007-07-05 — — US claimed
EP-1276804-B1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEM CO INC (US) 2006-06-14 — — EP claimed
US-20050282878-A1 Process for the purification of fluconazole GLENMARK PHARMACEUTICALS LIMITED (IN) 2005-12-22 — — US claimed
US-6706216-B1 REACTION PRODUCT OF CATALYTIC REDUCTIVE ALKYLATION OF P-PHENYLENEDIAMINE OR DERIVATIVE WITH ACETONE AND SECOND CARBONYL COMPOUND UNIROYAL CHEMICAL COMPANY, INC. 2004-03-16 — — US claimed
US-6706217-B2 OBTAINED FROM THE REACTION OF A PARAPHENYLENEDIAMINE COMPOUND WITH ACETONE AND AT LEAST ONE OF KETONES AND ALDEHYDES, USING A REDUCTIVE ALKYLATION CATALYST UNIROYAL CHEMICAL COMPANY, INC. 2004-03-16 — — US claimed
EP-1276804-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME Uniroyal Chemical Company, Inc. (US) 2003-01-22 — — EP claimed
US-20020061946-A1 Liquid antiozonants and rubber compositions containing same ADDIVANT USA, LLC 2002-05-23 — — US claimed
WO-2001081459-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-11-01 — — WO claimed
US-20260132232-A1 OPHTHALMIC DEVICES BAUSCH LOMB IRELAND LTD (IE) 2026-05-14 — — US disclosed
EP-3788084-B1 OPHTHALMIC DEVICES CONTAINING UV BLOCKER AND METHODS FOR THEIR PREPARATION BAUSCH & LOMB (US) 2026-04-29 — — EP disclosed
US-12552883-B2 Ophthalmic devices BAUSCH + LOMB IRELAND LIMITED (IE) 2026-02-17 — — US disclosed
EP-4677398-A1 CONTACT LENS CONTAINING DEPROTECTED ULTRAVIOLET BLOCKERS Bausch + Lomb Ireland Limited (IE) 2026-01-14 — — EP disclosed
EP-4646240-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING Bausch + Lomb Ireland Limited (IE) 2025-11-12 — — EP disclosed
US-20020061946-A1 Liquid antiozonants and rubber compositions containing same ADDIVANT USA, LLC 2002-05-23 — — US disclosed
WO-2001081459-A1 LIQUID ANTIOZONANTS AND RUBBER COMPOSITIONS CONTAINING SAME UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-11-01 — — WO disclosed
US-4900868-A Process for producing N,N'-disubstituted paraphenylene diamine mixtures by sequential reductive alkylation MONSANTO COMPANY (US) 1990-02-13 — — US disclosed
US-4556744-A Process for the production of ethanol and/or acetaldehyde by the metal catalysed liquid phase reaction of methanol, carbon monoxide and hydrogen in the presence of a solvent THE BRITISH PETROLEUM COMPANY P.L.C. (GB) 1985-12-03 — — US disclosed
EP-0084527-A2 Process for producing paraphenylenediamine mixtures MONSANTO COMPANY (US) 1983-07-27 — — EP disclosed
US-3954832-A 16-And 16,16-methyl and ethyl substituted PGA1 -type compounds THE UPJOHN COMPANY (US) 1976-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282878-A1 Process for the purification of fluconazole ERG28, CYP51A1, MAN2B1 ALDH1A1 790/4885CES1 1041/4885CES2 811/4885
US-20260132232-A1 OPHTHALMIC DEVICES MYO1G, CRY1, UACA ALDH1A1 2066/4885CES1 1624/4885CES2 3730/4885
US-20070155633-A1 Diaromatic amine derivatives as antioxidants C9, C5, C1S ALDH1A1 462/4885CES1 1483/4885CES2 1378/4885
US-12552883-B2 Ophthalmic devices ILK, MYLK, SMAD2 ALDH1A1 2118/4885CES1 3213/4885CES2 4234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.