Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792799 | 0.64 | CA2 (0.40) | CA2KDM4ECA12CA1CA4 | |
| SCHEMBL8285731 | 0.62 | PTGES (0.44) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL2353218 | 0.61 | ADRA1D (0.46) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL18740669 | 0.61 | PTGES (0.43) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL22827702 | 0.61 | CA2 (0.42) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL22827735 | 0.60 | CA2 (0.41) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL5184948 | 0.60 | SHMT2 (0.61) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL32667840 | 0.60 | MAPT (0.65) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL5183853 | 0.59 | CYP1A2 (0.43) | CA2KDM4EMAPTKMT2ACA12 | |
| SCHEMBL10727722 | 0.59 | ABCC8 (0.63) | CA2KDM4EMAPTKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-07-01 | — | — | US | disclosed |
| EP-2061777-A1 | BENZOÝ1,2,3¨THIADIAZINE DERIVATIVES | Egis Gyogyszergyar Nyilvánosan Múködó Részvénytársaság (HU) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008020255-A1 | BENZO[1,2,3]THIADIAZINE DERIVATIVES | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | SULT2A1, TPH1, CYP1A1 | CA2 1484/4885KDM4E 3186/4885MAPT 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.