Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR known ✓ | P00374 | 1/20 | 0.55 |
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.53 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.70 |
| ▸ | HNF4A | P41235 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.45 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.45 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810721 | 0.82 | ACMSD (1.00) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL2536183 | 0.82 | ACMSD (1.00) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL9245988 | 0.82 | ACMSD (0.78) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| Zinc Ion SCHEMBL9652815 | 0.81 | ACMSD (0.70) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL4216869 | 0.79 | ACMSD (0.72) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL7022773 | 0.79 | ACMSD (0.72) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL5381921 | 0.78 | ACMSD (0.70) | ACMSDHNF4AKDM4EALDH1A1HPGD | |
| SCHEMBL31556217 | 0.76 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1ALOX5 | |
| SCHEMBL18735541 | 0.76 | ACMSD (0.88) | ACMSDHNF4AKDM4EALDH1A1DHFR | |
| Salicylic Acid SCHEMBL5450889 | 0.76 | KDM4E (0.95) | KDM4EALDH1A1HPGDPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108219114-B | Halogen-free thermosetting resin composition, prepreg containing same, laminated board and printed circuit board | 广东生益科技股份有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-103773347-B | Improve oil recovery factor surfactant composition and preparation method thereof | SINOPEC CORP. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103773347-A | Surfactant combination for enhancing oil recovery and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | disclosed |