Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791341 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP1A2ABCC8KCNJ11KDM4E | |
| SCHEMBL2790682 | 0.78 | CA2 (0.37) | ALDH1A1ABCC8KCNJ11KDM4ELMNA | |
| SCHEMBL2793795 | 0.75 | PKM (0.34) | ALDH1A1CA2CA1CA12CA4 | |
| SCHEMBL3579238 | 0.66 | CA1 (0.35) | CA2CA1 | |
| SCHEMBL3588752 | 0.63 | ALDH1A1 (0.46) | ALDH1A1CYP1A2ABCC8KCNJ11KDM4E | |
| SCHEMBL2792778 | 0.62 | ALDH1A1 (0.38) | ALDH1A1CYP1A2ABCC8KCNJ11KDM4E | |
| SCHEMBL8285709 | 0.60 | ALDH1A1 (0.54) | ALDH1A1CYP1A2ABCC8KCNJ11KDM4E | |
| SCHEMBL13242322 | 0.59 | HTR2C (0.53) | ALDH1A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL10908011 | 0.58 | ALDH1A1 (0.49) | ALDH1A1CYP1A2ABCC8KCNJ11KDM4E | |
| SCHEMBL5621775 | 0.57 | CA12 (0.32) | CA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190778-A1 | 3,4-DIHYDROBENZO[1,2,3]THIADIAZINE-1,1-DIOXIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, MEDICAMENTS CONTAINING SAID DERIVATIVES AND THEIR USE | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENTARSASAG (HU) | 2010-07-29 | — | — | US | disclosed |
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-07-01 | — | — | US | disclosed |
| EP-2061777-A1 | BENZOÝ1,2,3¨THIADIAZINE DERIVATIVES | Egis Gyogyszergyar Nyilvánosan Múködó Részvénytársaság (HU) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008020255-A1 | BENZO[1,2,3]THIADIAZINE DERIVATIVES | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190778-A1 | 3,4-DIHYDROBENZO[1,2,3]THIADIAZINE-1,1-DIOXIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, MEDICAMENTS CONTAINING SAID DERIVATIVES AND THEIR USE | TDO2, DHODH, DHPS | ALDH1A1 45/4885CYP1A2 9/4885ABCC8 3443/4885 |
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | SULT2A1, TPH1, CYP1A1 | ALDH1A1 39/4885CYP1A2 10/4885ABCC8 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.