Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796293 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 | |
| SCHEMBL2793095 | 0.73 | HTR1A (0.35) | — | |
| SCHEMBL3575925 | 0.64 | ALDH1A1 (0.40) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 | |
| SCHEMBL3579238 | 0.63 | CA1 (0.35) | CA2CA1 | |
| SCHEMBL3587549 | 0.61 | GRIA2 (0.39) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 | |
| SCHEMBL3583177 | 0.59 | CA2 (0.37) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 | |
| SCHEMBL2792778 | 0.59 | ALDH1A1 (0.38) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 | |
| SCHEMBL2790682 | 0.58 | CA2 (0.37) | ALDH1A1LMNATSHRABCC8KCNJ11 | |
| SCHEMBL24090539 | 0.58 | CA1 (0.42) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL720640 | 0.58 | ALDH1A1 (0.66) | ALDH1A1CYP1A2LMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190778-A1 | 3,4-DIHYDROBENZO[1,2,3]THIADIAZINE-1,1-DIOXIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, MEDICAMENTS CONTAINING SAID DERIVATIVES AND THEIR USE | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENTARSASAG (HU) | 2010-07-29 | — | — | US | disclosed |
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-07-01 | — | — | US | disclosed |
| EP-2061777-A1 | BENZOÝ1,2,3¨THIADIAZINE DERIVATIVES | Egis Gyogyszergyar Nyilvánosan Múködó Részvénytársaság (HU) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008020255-A1 | BENZO[1,2,3]THIADIAZINE DERIVATIVES | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190778-A1 | 3,4-DIHYDROBENZO[1,2,3]THIADIAZINE-1,1-DIOXIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, MEDICAMENTS CONTAINING SAID DERIVATIVES AND THEIR USE | TDO2, DHODH, DHPS | ALDH1A1 45/4885CYP1A2 9/4885LMNA 3824/4885 |
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | SULT2A1, TPH1, CYP1A1 | ALDH1A1 39/4885CYP1A2 10/4885LMNA 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.