Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 17/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344192 | 0.90 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6353503 | 0.87 | PTGS2 (0.62) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL6432346 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6343036 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6342793 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL14029024 | 0.79 | PTGS2 (0.41) | PTGS2PTGS1ABCB11ALDH1A1 | |
| Cimicoxib SCHEMBL3123310 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Cimicoxib SCHEMBL29386198 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6344515 | 0.78 | PTGS2 (0.76) | PTGS2PTGS1ABCB11 | |
| SCHEMBL3245704 | 0.78 | PTGS2 (0.80) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724362-B2 | Pharmaceutical compositions comprising nanoparticles and a resuspending material | BEND RESEARCH, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-8974827-B2 | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer | BEND RESEARCH, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20100323014-A1 | NANOPARTICLES COMPRISING A NON-IONIZABLE CELLULOSIC POLYMER AND AN AMPHIPHILIC NON-IONIZABLE BLOCK COPOLYMER | PFIZER INC. | 2010-12-23 | — | — | US | disclosed |
| US-20100310663-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NANOPARTICLES AND A RESUSPENDING MATERIAL | LONZA BEND INC. | 2010-12-09 | — | — | US | disclosed |
| US-20100266692-A1 | NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN ANIONIC CELLULOSIC POLYMER | BEND RESEARCH, INC. | 2010-10-21 | — | — | US | disclosed |
| US-20100215747-A1 | NANOPARTICLES COMPRISING IONIZABLE, POORLY WATER SOLUBLE CELLULOSIC POLYMERS | BEND RESEARCH, INC. | 2010-08-26 | — | — | US | disclosed |
| US-20100080852-A1 | PHAMACEUTICAL COMPOSITION COMPRISING NANOPARTICLES AND CASEIN | BEND RESEARCH, INC. | 2010-04-01 | — | — | US | disclosed |
| US-20080260817-A1 | Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist | PFIZER INC. | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323014-A1 | NANOPARTICLES COMPRISING A NON-IONIZABLE CELLULOSIC POLYMER AND AN AMPHIPHILIC NON-IONIZABLE BLOCK COPOLYMER | LRBA, CEL, TNNC1 | PTGS2 3985/4885PTGS1 4155/4885ABCB11 269/4885 |
| US-20100266692-A1 | NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN ANIONIC CELLULOSIC POLYMER | CEL, TNNC1, MGAM | PTGS2 3620/4885PTGS1 3610/4885ABCB11 413/4885 |
| US-20100215747-A1 | NANOPARTICLES COMPRISING IONIZABLE, POORLY WATER SOLUBLE CELLULOSIC POLYMERS | CEL, GYS1, TNNC1 | PTGS2 3826/4885PTGS1 3919/4885ABCB11 561/4885 |
| US-20100310663-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NANOPARTICLES AND A RESUSPENDING MATERIAL | SUCLG2, SORD, ACMSD | PTGS2 2751/4885PTGS1 1909/4885ABCB11 73/4885 |
| US-20080260817-A1 | Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist | LTB4R2, LTB4R, LTC4S | PTGS2 12/4885PTGS1 21/4885ABCB11 3626/4885 |
| US-20100080852-A1 | PHAMACEUTICAL COMPOSITION COMPRISING NANOPARTICLES AND CASEIN | PACSIN2, CSNK1A1, CSNK1G1 | PTGS2 3446/4885PTGS1 2711/4885ABCB11 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.