Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL6275845 | 0.94 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylamide SCHEMBL3414684 | 0.92 | TSHR (0.48) | TSHRTHRBALDH1A1FGFR4POLB | |
| Acrylamide SCHEMBL7755621 | 0.89 | TSHR (0.46) | TSHRTHRBALDH1A1FGFR4POLB | |
| Acrylic Acid Methyl Ester SCHEMBL28138454 | 0.85 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid SCHEMBL27396381 | 0.85 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylamide SCHEMBL27510919 | 0.82 | TSHR (0.51) | TSHRTHRBALDH1A1FGFR4POLB | |
| SCHEMBL9687198 | 0.81 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL28472155 | 0.81 | THRB (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid SCHEMBL10944277 | 0.80 | TSHR (0.68) | TSHRTHRBALDH1A1FGFR4 | |
| Acrylic Acid SCHEMBL3447729 | 0.80 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104260480-A | Tin-plated steel and plastic composite copper band | WUXI YIMING PREC COPPERBELT CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-104194710-A | Elastic waterstop sealant for concrete joint | WUXI HITXINCHENG POLYMER TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-206791802-U | The anti-pin marched that born a heavy burden for high intensity steeps shoe-pad | 中国人民解放军南京军区福州总医院 | 2017-12-26 | — | — | CN | disclosed |
| CN-104260480-A | Tin-plated steel and plastic composite copper band | WUXI YIMING PREC COPPERBELT CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-104194710-A | Elastic waterstop sealant for concrete joint | WUXI HITXINCHENG POLYMER TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-104194710-A | Elastic waterstop sealant for concrete joint | WUXI HITXINCHENG POLYMER TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | disclosed |