Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27995136 | 0.94 | TSHR (0.42) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid Methyl Ester SCHEMBL28138454 | 0.91 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid SCHEMBL27396381 | 0.91 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9687198 | 0.87 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL28472155 | 0.87 | THRB (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid SCHEMBL27980474 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylic Acid SCHEMBL3447729 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Propene SCHEMBL10531877 | 0.85 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Propene SCHEMBL10530371 | 0.85 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Propene SCHEMBL6739183 | 0.85 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272406-B | Polymer composition for use as soil amendment with increased water absorption during crop watering | 聚合物绿色有限责任公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-113272406-A | Polymer composition for use as soil amendment with increased water absorption during crop watering | 聚合物绿色有限责任公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-106587398-A | Composite scale and corrosion inhibitor containing sodium polyepoxysuccinate and preparation method thereof | 陕西蔚然青科技有限公司 | 2017-04-26 | — | — | CN | disclosed |
| EP-1291334-B1 | Anti-bonding agents and methods for blast furnace slag or its grading adjusted slag | TAKEMOTO OIL & FAT CO LTD (JP) | 2013-10-23 | — | — | EP | disclosed |
| CN-1239528-C | Anti-coagulation agent and anti-coagulation method for blast furnace water granulated slag or particle size adjustment thereof | STEEL PIPE & MINING INDUSTRY C (JP) | 2006-02-01 | — | — | CN | disclosed |
| US-6936673-B2 | Anti-bonding methods for blast furnace slag or its grading adjusted slag | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2005-08-30 | — | — | US | disclosed |
| US-20050065306-A1 | Anti-bonding methods for blast furnace slag or its grading adjusted slag | KOKAN MINING CO., LTD., A CORPORATION OF JAPAN | 2005-03-24 | — | — | US | disclosed |
| US-20030110896-A1 | Anti-bonding agents and methods for blast furnace slag or its grading adjusted slag | KOKAN MINING CO., LTD. | 2003-06-19 | — | — | US | disclosed |
| CN-1407118-A | Anti-coagulation agent and anti-coagulation method for blast furnace water granulated slag or particle size adjustment thereof | STEEL PIPE & MINING INDUSTRY C (JP) | 2003-04-02 | — | — | CN | disclosed |
| EP-1291334-A2 | Anti-bonding agents and methods for blast furnace slag or its grading adjusted slag | Takemoto Yushi Kabushiki Kaisha (JP) | 2003-03-12 | — | — | EP | disclosed |