SCHEMBL2801701

SCHEMBL2801701

CC(C)c1ncnc(C(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12051510 0.87 SORD (0.31)
SCHEMBL2625488 0.84 NFKB1 (0.31)
SCHEMBL21153211 0.84
SCHEMBL21400714 0.84 ADORA2A (0.37) POLBHRH4
SCHEMBL14572429 0.81 EGFR (0.32) HRH4
SCHEMBL19050223 0.81 ALDH1A1 (0.33)
SCHEMBL13333647 0.81
SCHEMBL19367730 0.81 CYP1A2 (0.36)
SCHEMBL15215098 0.81 POLB (0.31) POLB
SCHEMBL16922209 0.79 F2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668898-B1 METHOD OF SEALING OFF WATER-INFLUX POINTS IN ROCK FORMATIONS BERGWERKSVERBAND GMBH (DE) 1997-03-12 EP claimed
EP-0656917-B1 PROCESS FOR USING A SYNTHETIC RESIN SYSTEM BERGWERKSVERBAND GMBH (DE) 1997-03-12 EP claimed
WO-2025088285-A1 ECOBIOLOGICAL TOPICAL COMPOSITION FOR TREATING SKIN REDNESS AND DISCOMFORT NAOS INSTITUTE OF LIFE SCIENCE (FR) 2025-05-01 WO disclosed
US-20240238304-A1 Small Molecule Degraders of DOT1L and Uses Thereof NORTHWESTERN UNIVERSITY 2024-07-18 US disclosed
US-20240238304-A1 Small Molecule Degraders of DOT1L and Uses Thereof NORTHWESTERN UNIVERSITY 2024-07-18 US disclosed
US-20240226106-A1 INHIBITORS OF PLASMA KALLIKREIN SHIRE HUMAN GENETIC THERAPIES (US) 2024-07-11 US disclosed
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN TAKEDA PHARMACEUTICALS CO (JP) 2024-07-11 US disclosed
US-20230295457-A1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-21 US disclosed
US-20230272143-A1 SURFACE TREATMENT LIQUID AND HYDROPHILIZING TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-31 US disclosed
US-20230159556-A1 NOVEL PROTEIN KINASE INHIBITORS TENOVA PHARMACEUTICALS INC. 2023-05-25 US disclosed
US-20220153751-A1 BIFUNCTIONAL COMPOUNDS BIOTHERYX, INC. (US) 2022-05-19 US disclosed
US-20090251049-A1 Organic electroluminescent device utilizing organic electroluminescent compounds GRACEL DISPLAY INC. (KR) 2009-10-08 US disclosed
US-20090189519-A1 Organic electroluminescent compounds and light emitting diode using the same GRACEL DISPLAY INC. (KR) 2009-07-30 US disclosed
US-20090069305-A1 Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-12 US disclosed
US-20090005399-A1 Substituted Imidazo[2,1-b]thiazole Compounds and Uses Thereof GRUENENTHAL GMBH (DE) 2009-01-01 US disclosed
US-20080242702-A1 Paclitaxel enhancer compound SYNTA PHARMACEUTICALS CORP. 2008-10-02 US disclosed
US-20080214655-A1 Paclitaxel enhancer compounds SYNTA PHARMACEUTICALS CORP. 2008-09-04 US disclosed
US-7368473-B2 Paclitaxel enhancer compounds SYNTA PHARMACEUTICALS CORP. (US) 2008-05-06 US disclosed
US-7345094-B2 Paclitaxel enhancer compounds SYNTA PHARMACEUTICALS CORP. (US) 2008-03-18 US disclosed
US-5429949-A S-triazine degrading bacteria OHIO STATE RESEARCH FOUNDATION (US) 1995-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090189519-A1 Organic electroluminescent compounds and light emitting diode using the same OCIAD1, AOX1, OCIAD2 POLB 899/4885HRH4 2734/4885
US-20090005399-A1 Substituted Imidazo[2,1-b]thiazole Compounds and Uses Thereof GRM5, GRIK5, GRM1 POLB 4542/4885HRH4 209/4885
US-20090251049-A1 Organic electroluminescent device utilizing organic electroluminescent compounds OCIAD2, OCIAD1, LAGE3 POLB 907/4885HRH4 4480/4885
US-20090069305-A1 Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor HRH4, HRH3, HRH2 POLB 4593/4885HRH4 1/4885
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK5, KLK1 POLB 4692/4885HRH4 1751/4885
US-20230159556-A1 NOVEL PROTEIN KINASE INHIBITORS ERBB2, ALK, ERBB3 POLB 3016/4885HRH4 4393/4885
US-20240226106-A1 INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK5, KLK1 POLB 4699/4885HRH4 1063/4885
US-20080242702-A1 Paclitaxel enhancer compound CENPE, FOXM1, C9 POLB 2310/4885HRH4 73/4885
US-20240238304-A1 Small Molecule Degraders of DOT1L and Uses Thereof DOT1L, STUB1, BAZ2B POLB 3306/4885HRH4 4567/4885
US-20080214655-A1 Paclitaxel enhancer compounds ABCC8, FOXM1, C9 POLB 1858/4885HRH4 93/4885
US-20220153751-A1 BIFUNCTIONAL COMPOUNDS CDK2, CDK6, CDK5 POLB 230/4885HRH4 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.