Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.42 |
| ▸ | IDH2 | P48735 | 4/20 | 0.41 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022383 | 0.94 | SFRP1 (0.44) | PDK1PDK2PDK3PDK4SFRP1 | |
| SCHEMBL28022378 | 0.90 | PDK1 (0.39) | PDK1PDK2PDK3PDK4SFRP1 | |
| SCHEMBL2195206 | 0.76 | CCR2 (0.46) | — | |
| SCHEMBL2195213 | 0.76 | CCR2 (0.46) | — | |
| SCHEMBL28022895 | 0.76 | MMP7 (0.40) | — | |
| SCHEMBL28022345 | 0.73 | PTGS2 (0.44) | — | |
| SCHEMBL17393831 | 0.73 | — | — | |
| SCHEMBL17393829 | 0.73 | — | — | |
| SCHEMBL1723222 | 0.73 | UCHL1 (0.54) | IDH2PIK3CDPIK3CAPIK3CBMTOR | |
| SCHEMBL1722677 | 0.72 | KDM4E (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |