SCHEMBL28038799

SCHEMBL28038799

O=S(=O)([O-])CCc1ccccc1.[Na+]

nearest known ligand 0.53

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 5/20 0.52
CA12 known ✓ O43570 2/20 0.45
CA1 known ✓ P00915 2/20 0.44
IDO1 P14902 1/20 0.48
CA9 Q16790 2/20 0.45
CA7 P43166 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
LMNA P02545 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
MMP1 P03956 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11701740 0.98 CA2 (0.53) CA2IDO1CA12CA9CA1
SCHEMBL6962827 0.95 CA2 (0.52) CA2IDO1CA12CA9CA1
SCHEMBL28294568 0.87 CA2 (0.55) CA2HDAC3HDAC4HDAC1HDAC7
SCHEMBL11091813 0.84 CA2 (0.51) CA2HDAC3HDAC4HDAC1HDAC7
SCHEMBL8855379 0.83 MGLL (0.59) CA2CA12CA9CA1CA7
SCHEMBL10973386 0.79 CA2 (0.51) CA2
SCHEMBL4704220 0.78 TAAR1 (0.45) CA2CA12CA9CA1CA7
SCHEMBL6579256 0.78 TAAR1 (0.45) CA2CA12CA9CA1CA7
SCHEMBL2377550 0.78 TAAR1 (0.45) CA2IDO1CA12CA9CA1
SCHEMBL9343853 0.78 KMT2A (0.56) CA2CA1CA7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113637964-A Preparation method of anti-oxidation treatment fluid for end face of battery copper foil 新疆亿日铜箔科技股份有限公司 2021-11-12 CN claimed
CN-105149185-A Method for preparing super-hydrophobic compound thin film with micro and nano structure WUXI QIAOYANG MACHINERY MFG CO LTD 2015-12-16 CN claimed
CN-115926067-B High-temperature-resistant hyperbranched retarder for concrete and preparation method thereof 科之杰新材料集团有限公司 2024-09-03 CN disclosed
CN-115926067-A High-temperature-resistant hyperbranched retarder for concrete and preparation method thereof 科之杰新材料集团有限公司 2023-04-07 CN disclosed
CN-113637964-A Preparation method of anti-oxidation treatment fluid for end face of battery copper foil 新疆亿日铜箔科技股份有限公司 2021-11-12 CN disclosed
CN-113637964-A Preparation method of anti-oxidation treatment fluid for end face of battery copper foil 新疆亿日铜箔科技股份有限公司 2021-11-12 CN disclosed
CN-105149185-A Method for preparing super-hydrophobic compound thin film with micro and nano structure WUXI QIAOYANG MACHINERY MFG CO LTD 2015-12-16 CN disclosed