Sugi Predict

Sugi Predict / Compounds / SCHEMBL2804478

SCHEMBL2804478

SCHEMBL2804478

Cc1nc(C(=O)O)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ KDM4E B2RXH2 3/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ ALDH1A1 P00352 4/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ ASPH Q12797 2/20 0.40
▸ KDM8 Q8N371 1/20 0.40
▸ GABRP O00591 1/20 0.40
▸ GABRD O14764 1/20 0.40
▸ GABRA1 P14867 1/20 0.40
▸ GABRB1 P18505 1/20 0.40
▸ GABRG2 P18507 1/20 0.40
▸ GABRB3 P28472 1/20 0.40
▸ GABRA5 P31644 1/20 0.40
▸ GABRA3 P34903 1/20 0.40
▸ GABRA2 P47869 1/20 0.40
▸ GABRB2 P47870 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415461 1.00 ALOX15 (0.43) ALOX15TSHRHIF1AKDM4EKMT2A
SCHEMBL4746949 0.82 ALDH1A1 (0.50) ALOX15TSHRHIF1AKDM4EKMT2A
SCHEMBL8874266 0.82 ALDH1A1 (0.50) TSHRKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL23884906 0.82 ALOX15 (0.45) ALOX15TSHRHIF1AKDM4EKMT2A
SCHEMBL31633618 0.82 ALDH1A1 (0.50) TSHRKDM4EKMT2AALDH1A1SMN1; SMN2
SCHEMBL2807043 0.78 KDM4E (0.48) ALOX15TSHRHIF1AKDM4EKMT2A
SCHEMBL8004712 0.78 ALOX15 (0.45) ALOX15TSHRHIF1AKDM4EL3MBTL1
SCHEMBL2810386 0.76 SMN1; SMN2 (0.43) KDM4EKMT2AALDH1A1SMN1; SMN2GABRP
SCHEMBL2808534 0.76 KDM4E (0.47) KDM4EKMT2AALDH1A1SMN1; SMN2GABRP
SCHEMBL2807003 0.76 ALDH1A1 (0.40) KDM4EKMT2AL3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
WO-2013019834-A1 DEGRADABLE SIX PACK RINGS AND COMPOSITIONS AND METHODS RELATING THERETO MYRIANT CORPORATION (US) 2013-02-07 — — WO claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
US-12312440-B2 Glycolic acid polymer SYENSQO SA (BE) 2025-05-27 — — US disclosed
EP-3559081-B1 GLYCOLIC ACID POLYMER SOLVAY (BE) 2023-11-22 — — EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 — — CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 — — US disclosed
CN-110088167-B Glycolic acid polymers 索尔维公司 2022-02-08 — — CN disclosed
US-20200190255-A1 GLYCOLIC ACID POLYMER SYENSQO SA (BE) 2020-06-18 — — US disclosed
EP-3559081-A1 GLYCOLIC ACID POLYMER Solvay SA (BE) 2019-10-30 — — EP disclosed
CN-110088167-A Glycolic acid polymer 索尔维公司 2019-08-02 — — CN disclosed
WO-2018115008-A1 GLYCOLIC ACID POLYMER SOLVAY SA (BE) 2018-06-28 — — WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed
EP-0829503-B1 Degradable polymer and preparation process of the same MITSUI CHEMICALS INC (JP) 2002-04-03 — — EP disclosed
US-5914381-A Degradable polymer and preparation process of the same MITSUI CHEMICALS, INC. (JP) 1999-06-22 — — US disclosed
EP-0829503-A2 Degradable polymer and preparation process of the same MITSUI TOATSU CHEMICALS, INC. (JP) 1998-03-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALOX15 914/4885TSHR 4385/4885HIF1A 2635/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB ALOX15 608/4885TSHR 4263/4885HIF1A 2697/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALOX15 383/4885TSHR 2885/4885HIF1A 1087/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA ALOX15 1704/4885TSHR 3021/4885HIF1A 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.