Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046664 | 0.86 | MAP4K4 (0.46) | KMOCHEK2MAPTNUDT1CCNC | |
| SCHEMBL28046684 | 0.81 | KMO (0.44) | KMOGAAMAPTNUDT1MEN1 | |
| SCHEMBL28046677 | 0.81 | ALPL (0.45) | CHEK2MAPTCCNCCDK8 | |
| SCHEMBL28046609 | 0.81 | CASP1 (0.43) | CHEK2NUDT1 | |
| SCHEMBL28046616 | 0.81 | PARP1 (0.47) | CHEK2KDM4ENPC1RAB9A | |
| SCHEMBL28046611 | 0.79 | MAPT (0.54) | KDM4EPOLBGAAMAPTMEN1 | |
| SCHEMBL28046610 | 0.77 | ROCK2 (0.54) | KDM4EGAAMAPTMEN1NPC1 | |
| SCHEMBL28046665 | 0.77 | HPGDS (0.51) | KMOCHEK2KDM4EMAPTNUDT1 | |
| SCHEMBL28046612 | 0.77 | DHODH (0.46) | KMONUDT1 | |
| SCHEMBL28046613 | 0.76 | CDK5 (0.41) | CHEK2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294688-A | 6-chlorine-N-(substituted benzyl)-1H-pyrrolo[2,3-b]pyridine-2-amide compound and preparation method as well as application thereof | UNIV BEIJING TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |