Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.42 |
| ▸ | CA9 | Q16790 | 9/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053334 | 0.77 | IKBKB (0.35) | PKMALDH1A1TDP2NSD2CA1 | |
| SCHEMBL28053258 | 0.73 | PKM (0.46) | PKMPOLBGAAMAPTALDH1A1 | |
| SCHEMBL29902406 | 0.69 | PKM (0.62) | PKMPOLBGAAMAPTALDH1A1 | |
| SCHEMBL8349082 | 0.66 | LMNA (0.67) | PKMPOLBGAAMAPTALDH1A1 | |
| SCHEMBL11117720 | 0.66 | CA2 (0.59) | PKMGAAMAPTALDH1A1CA1 | |
| SCHEMBL1803937 | 0.66 | PTGS1 (0.66) | PKMGAAMAPTCA1CA2 | |
| SCHEMBL4709444 | 0.66 | TDP1 (0.60) | PKMPOLBGAAMAPTCA1 | |
| SCHEMBL10775524 | 0.66 | TDP2 (0.67) | PKMPOLBGAAMAPTALDH1A1 | |
| SCHEMBL7339146 | 0.66 | TDP2 (0.67) | PKMPOLBGAAMAPTALDH1A1 | |
| SCHEMBL27954272 | 0.65 | PKM (0.51) | PKMPOLBGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | claimed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |