Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064167 | 0.88 | KCNA5 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL28064079 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1TDP1NPBWR1SMN1; SMN2 | |
| SCHEMBL2231167 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1TDP1HTTRECQL | |
| SCHEMBL28064076 | 0.79 | PPARG (0.47) | TSHR | |
| SCHEMBL28088135 | 0.77 | PPARG (0.40) | KDM4EALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL28064164 | 0.77 | SIGMAR1 (0.38) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28064061 | 0.76 | PPARG (0.37) | MCHR1MAPT | |
| SCHEMBL28064074 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28064161 | 0.76 | HCRTR1 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL28064165 | 0.75 | CHEK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |