Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.47 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384966 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2384323 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2384446 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL621494 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL891108 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2383941 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| Lithium Ion SCHEMBL10589843 | 0.96 | GPR84 (0.45) | GPR84CA2FFAR1TP53CA1 | |
| SCHEMBL8385329 | 0.96 | GPR84 (0.45) | GPR84CA2FFAR1TP53CA1 | |
| SCHEMBL11431285 | 0.89 | FFAR1 (0.50) | FFAR1RECQLEPHX2BLMFFAR4 | |
| SCHEMBL3022383 | 0.85 | FABP3 (0.50) | FFAR1NFKB1HPGDTSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105950127-B | Viscous crude pour-viscosity reduction composition, viscous crude pour point depression and viscosity reduction agent and preparation method thereof | 中国石油化工股份有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-105950127-A | Pour point depressing and viscosity reducing composition for heavy oil, pour point depressing and viscosity reducing agent for heavy oil and preparation method of pour point depressing and viscosity reducing agent | 中国石油化工股份有限公司 | 2016-09-21 | — | — | CN | disclosed |