Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.47 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384966 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL28088262 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2384323 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2384446 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL621494 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| SCHEMBL2383941 | 1.00 | GPR84 (0.47) | GPR84CA2FFAR1NFKB1RECQL | |
| Lithium Ion SCHEMBL10589843 | 0.96 | GPR84 (0.45) | GPR84CA2FFAR1TP53CA1 | |
| SCHEMBL8385329 | 0.96 | GPR84 (0.45) | GPR84CA2FFAR1TP53CA1 | |
| SCHEMBL11431285 | 0.89 | FFAR1 (0.50) | FFAR1RECQLEPHX2BLMFFAR4 | |
| SCHEMBL3022383 | 0.85 | FABP3 (0.50) | FFAR1NFKB1HPGDTSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457863-B2 | Composition of an organic foaming additive for high temperature and high salinity | INSTITUTO MEXICANO DEL PETRÓLEO (MX) | 2019-10-29 | — | — | US | claimed |
| CN-102524265-B | Nano-scale dispersion system suspending agent for paclobutrazol, and preparation method thereof | UNIV LIAONING NORMAL | 2014-04-23 | — | — | CN | claimed |
| CN-102524265-A | Nano-scale dispersion system suspending agent for paclobutrazol, and preparation method thereof | UNIV LIAONING NORMAL | 2012-07-04 | — | — | CN | claimed |
| CN-1111161-C | Diacetal composition, process for preparation of same, nucleating agent for polyolefins contg. same, polyolefin resin compositions, and moldings | NEW JAPAN CHEM CO LTD (JP) | 2003-06-11 | — | — | CN | claimed |
| CN-1241190-A | Diacetal composition, process for producing the same, polyolefin nucleating agent containing said composition, polyolefin resin composition and molded article | NEW JAPAN CHEM CO LTD (JP) | 2000-01-12 | — | — | CN | claimed |
| JP-60019774-A | — | — | None | — | — | JP | disclosed |
| EP-3728487-B1 | METHOD OF REMOVING POLYMERIC MATERIAL COMPRISING HETEROATOMS FROM A SURFACE USING COMPOSITIONS INCLUDING A KETO-ESTER COMPOUND | FOURTH PRINCIPLE LLC (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20230049362-A1 | NATIVE AND POROUS STARCH AS WHITE PIGMENT IN TOOTHPASTE | ROQUETTE FRERES (FR) | 2023-02-16 | — | — | US | disclosed |
| EP-4090312-A1 | NATIVE AND POROUS STARCH AS WHITE PIGMENT IN TOOTHPASTE | ROQUETTE FRERES (FR) | 2022-11-23 | — | — | EP | disclosed |
| CN-115003277-A | Natural and porous starch as white pigment in toothpaste | 罗盖特公司 | 2022-09-02 | — | — | CN | disclosed |
| US-11370996-B2 | Compositions including keto-ester compounds and methods of using the same | FOURTH PRINCIPLE, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| WO-2021144245-A1 | NATIVE AND POROUS STARCH AS WHITE PIGMENT IN TOOTHPASTE | ROQUETTE FRERES (FR) | 2021-07-22 | — | — | WO | disclosed |
| EP-0648740-B1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0755927-A1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |
| US-5574064-A | Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0648740-A1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0339498-A2 | Liquid detergent composition | AJINOMOTO CO., INC. (JP) | 1989-11-02 | — | — | EP | disclosed |
| JP-S6019774-A | GRANULATION OF COMPOSITION CONTAINING CHLORINATED ISOCYANURIC ACID | NISSAN CHEM IND LTD | 1985-01-31 | — | — | JP | disclosed |
| US-4197347-A | High density magnetic recording media | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4063000-A | Process for production of ferromagnetic powder | FUJI PHOTO FILM CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |