Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 0.43 |
| ▸ | ADORA2A known ✓ | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B known ✓ | P29275 | 2/20 | 0.42 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.42 |
| ▸ | P2RY1 known ✓ | P47900 | 1/20 | 0.41 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406383 | 0.91 | TP53 (0.47) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL4229799 | 0.80 | ALDH1A1 (0.44) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL3208247 | 0.80 | TP53 (0.51) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL136036 | 0.80 | TP53 (0.51) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL6704178 | 0.80 | TP53 (0.51) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL40771 | 0.79 | TP53 (0.50) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL5317002 | 0.79 | TP53 (0.50) | TP53ALDH1A1HTTBLMGMNN | |
| SCHEMBL965396 | 0.79 | ADORA2A (0.52) | ADORA3ADORA2AADORA2BSLC29A1ADORA1 | |
| SCHEMBL9673911 | 0.78 | SLC29A1 (0.50) | TP53BLMLMNARAB9ASMN1; SMN2 | |
| SCHEMBL2448088 | 0.78 | P2RY1 (0.48) | BLMLMNAPMP22ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100239621-A1 | GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2210583-A1 | GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME | FUJIFILM Corporation (JP) | 2010-07-28 | — | — | EP | disclosed |