SCHEMBL28098701

SCHEMBL28098701

CCN(CC)C(=O)Cc1[c]cccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.40
HPGD P15428 3/20 0.40
GLA P06280 1/20 0.40
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HCRTR2 O43614 1/20 0.39
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3769274 0.82 NR4A2 (0.38) HSD17B10KDM4EHPGDNPC1RAB9A
SCHEMBL3759361 0.79 ACHE (0.40) KDM4ELMNACYP1A2CYP3A4CYP2D6
SCHEMBL10434783 0.77 PKM (0.45) HSD17B10KDM4ERECQLLMNATSHR
SCHEMBL9311840 0.76 ALDH1A1 (0.36) KDM4EHPGDLMNATSHRCYP1A2
SCHEMBL28496629 0.74 NPC1 (0.58) TSPOHPGDNPC1RAB9AALDH1A1
SCHEMBL1521437 0.74 AKR1B1 (0.48) HSD17B10KDM4EHPGDGLATDP1
SCHEMBL11426963 0.72 NLRP3 (0.43) HSD17B10KDM4EGLALMNANPSR1
SCHEMBL8749753 0.72 RAB9A (0.54) TSPOKDM4ETDP1NPC1RAB9A
SCHEMBL27524135 0.72 LTB4R (0.53)
SCHEMBL2209032 0.72 CA2 (0.38) HSD17B10KDM4EHPGDRECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN claimed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN disclosed
CN-112458624-A Preparation method of non-woven fabric material with mite removing function 杭州靖舒新材料有限公司 2021-03-09 CN disclosed
CN-105873908-A Novel compounds for combating arthropods 拜耳作物科学股份公司 2016-08-17 CN disclosed