Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103279 | 0.82 | ALOX5 (0.46) | NOTUMDRD2DRD3ADRB1 | |
| SCHEMBL28103298 | 0.79 | DRD2 (0.48) | DRD2DRD3ADRB1MEN1KMT2A | |
| SCHEMBL28103616 | 0.74 | HTR3E (0.43) | DRD2DRD4 | |
| SCHEMBL28103632 | 0.72 | ALOX5 (0.46) | HTR2AHTR2CHTR1ASLC6A2DRD2 | |
| SCHEMBL28835067 | 0.72 | ALOX5 (0.49) | DRD2ADRB1MEN1KMT2A | |
| SCHEMBL28103546 | 0.71 | MGLL (0.35) | — | |
| SCHEMBL28103584 | 0.70 | FAAH (0.40) | P2RX7HTR1ADRD2 | |
| SCHEMBL27743313 | 0.70 | ALOX5 (0.48) | NOTUMHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL4915902 | 0.69 | ADRB1 (0.64) | HTR2AHTR2CHTR1ASLC6A2DRD2 | |
| SCHEMBL27380663 | 0.67 | ALOX5 (0.44) | NOTUMADRB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |