Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103609 | 0.82 | NOTUM (0.38) | ADRB1NOTUMDRD2DRD3 | |
| SCHEMBL28103546 | 0.81 | MGLL (0.35) | MGLLHCAR1L3MBTL1 | |
| SCHEMBL28103632 | 0.80 | ALOX5 (0.46) | ALOX5MGLLDRD2DRD3HCAR1 | |
| SCHEMBL28103584 | 0.78 | FAAH (0.40) | MGLLDRD2ALDH1A1HCAR1MAPT | |
| SCHEMBL28103538 | 0.78 | NCF1 (0.38) | ALOX5 | |
| SCHEMBL28103298 | 0.78 | DRD2 (0.48) | ADRB1MGLLDRD2DRD3ALDH1A1 | |
| SCHEMBL27671224 | 0.77 | ALOX5 (0.41) | ALOX5ADRB1NOTUMRAB9AGAA | |
| SCHEMBL27380663 | 0.74 | ALOX5 (0.44) | ALOX5ADRB1NOTUMAKR1C3 | |
| SCHEMBL28039321 | 0.74 | ADRB1 (0.45) | ADRB1NOTUMALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27743313 | 0.74 | ALOX5 (0.48) | ALOX5ADRB1NOTUMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |