SCHEMBL2811192

SCHEMBL2811192

O=C(O)C1CNCC1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.43
SLC1A2 P43004 2/20 0.40
TSHR P16473 3/20 0.39
PMP22 Q01453 2/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39
GABRE P78334 1/20 0.39
GABRA6 Q16445 1/20 0.39
GABRG1 Q8N1C3 1/20 0.39
GABRG3 Q99928 1/20 0.39
GABRQ Q9UN88 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221050 1.00 GABRR1 (0.43) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL22160590 1.00 GABRR1 (0.43) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL6335676 1.00 GABRR1 (0.43) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL4445650 1.00 GABRR1 (0.43) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL21402232 0.97 GABRR1 (0.41) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL17743462 0.97 GABRR1 (0.41) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL29951639 0.87 HPSE (0.37) GABRR1SLC1A2TSHRMC4RLMNA
SCHEMBL11889143 0.85 SLC1A2 (0.38) GABRR1SLC1A2TSHRPMP22GABRP
SCHEMBL3196556 0.83
SCHEMBL10179391 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449569-B Preparation method and application of keratin-based high-performance filler reinforced acrylic resin retanning agent 兴业皮革科技股份有限公司 2025-04-22 CN claimed
CN-115449569-A Preparation method and application of high-performance filler reinforced acrylic resin retanning agent based on keratin 兴业皮革科技股份有限公司 2022-12-09 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
CN-106967213-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2019-11-05 CN claimed
US-10227302-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2019-03-12 US claimed
US-20180222863-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2018-08-09 US claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-20070007489-A1 Heat transfer medium composition SHISHIAI-KABUSHIKIGAISHA (JP) 2007-01-11 US claimed
EP-1698678-A1 HEAT CARRIER COMPOSITION Shishiai-Kabushikigaisha (JP) 2006-09-06 EP claimed
CN-115449569-B Preparation method and application of keratin-based high-performance filler reinforced acrylic resin retanning agent 兴业皮革科技股份有限公司 2025-04-22 CN disclosed
CN-115449569-B Preparation method and application of keratin-based high-performance filler reinforced acrylic resin retanning agent 兴业皮革科技股份有限公司 2025-04-22 CN disclosed
WO-2025052278-A1 PYRROLIDINE BASED CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS GENEVANT SCIENCES GMBH (CH) 2025-03-13 WO disclosed
CN-109666160-B Dynamic polymer with hybrid cross-linked network 厦门天策材料科技有限公司 2023-07-14 CN disclosed
US-20050215599-A1 Pyrrolidine-3,4-dicarboxamide derivatives F. HOFFMANN-LA ROCHE AG (CH) 2005-09-29 US disclosed
WO-2005037826-A1 SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES INCYTE CORPORATION (US) 2005-04-28 WO disclosed
US-6858626-B2 Enzyme inhibitor; antiinflammatory agents; osteoporosis BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-02-22 US disclosed
US-20030139597-A1 Novel Cyclic hydroxamic acid as metalloproteinase inhibitors XUE CHU-BIAO (US) 2003-07-24 US disclosed
US-6429213-B1 ANTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215599-A1 Pyrrolidine-3,4-dicarboxamide derivatives F9, F2, F12 GABRR1 2352/4885SLC1A2 2466/4885TSHR 1530/4885
US-20030139597-A1 Novel Cyclic hydroxamic acid as metalloproteinase inhibitors MMP9, MMP2, MMP25 GABRR1 1693/4885SLC1A2 649/4885TSHR 3243/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 GABRR1 2665/4885SLC1A2 4244/4885TSHR 4385/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA GABRR1 2370/4885SLC1A2 3491/4885TSHR 2885/4885
US-20180222863-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY L3MBTL1, L3MBTL3, RNASEH1 GABRR1 2313/4885SLC1A2 1111/4885TSHR 871/4885
US-10227302-B2 Ionizable cationic lipid for RNA delivery L3MBTL1, L3MBTL3, RNASEH1 GABRR1 2313/4885SLC1A2 1111/4885TSHR 871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.