Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cloprostenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.84 |
| ▸ | ABCC4 | O15439 | 2/20 | 1.00 |
| ▸ | PTGFR | P43088 | 16/20 | 0.84 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.84 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.84 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cloprostenol SCHEMBL28077016 | 1.00 | ABCC4 (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL29600088 | 1.00 | ABCC4 (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL29709332 | 1.00 | ABCC4 (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL28850753 | 1.00 | ABCC4 (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Delprostenate SCHEMBL8206607 | 0.92 | ABCC4 (0.84) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL17200671 | 0.92 | PTGFR (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL15390430 | 0.92 | PTGFR (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL123595 | 0.92 | PTGFR (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL123596 | 0.92 | PTGFR (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 | |
| Cloprostenol SCHEMBL14913508 | 0.92 | PTGFR (1.00) | ABCC4PTGFRPTGER3TBXA2RPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2264 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3232171-B1 | ILLUMINATION DEVICE AND REFLECTION CHARACTERISTICS MEASUREMENT DEVICE | KONICA MINOLTA INC (JP) | 2024-06-12 | — | — | EP | claimed |
| EP-3503939-B1 | BLOOD PUMP ASSEMBLY | NUPULSECV INC (US) | 2023-11-29 | — | — | EP | claimed |
| EP-3361542-B1 | ZIRCONIA ELECTROLYTE AND METHOD FOR PRODUCING ZIRCONIA ELECTROLYTE | NIPPON CATALYTIC CHEM IND (JP) | 2023-07-05 | — | — | EP | claimed |
| WO-2022269228-A1 | HAIR STYLING APPLIANCE | DYSON TECHNOLOGY LIMITED (GB) | 2022-12-29 | — | — | WO | claimed |
| US-20220193711-A1 | VEHICLE WHEEL DECORATION METHOD AND DECORATION DEVICE | BBS JAPAN CO., LTD. (JP) | 2022-06-23 | — | — | US | claimed |
| CN-113331132-B | Treatment method for improving summer reproduction rate and milk yield of dairy cows by adopting capsaicin | 华中农业大学 | 2022-06-21 | — | — | CN | claimed |
| EP-3957406-A1 | VEHICLE WHEEL DECORATION METHOD AND DECORATION DEVICE | BBS Japan Co., LTD (JP) | 2022-02-23 | — | — | EP | claimed |
| EP-3852608-A1 | COMPOSITIONS AND METHODS FOR GLAUCOMA | Aufbau Medical Innovations Limited (IE) | 2021-07-28 | — | — | EP | claimed |
| CN-113016717-A | Ultrashort-period synchronous estrus-producing method for sheep | 河北农业大学 | 2021-06-25 | — | — | CN | claimed |
| US-20210178489-A1 | DIAMOND-COATED TOOL | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-06-17 | — | — | US | claimed |
| WO-1999012550-A1 | METHOD OF INCREASING BONE VOLUME | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-18 | — | — | WO | claimed |
| WO-1997036727-A2 | SYSTEM AND METHOD FOR INJECTION MOLDING | NYPRO, INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0517588-B1 | Transient suppression component | AMPHENOL CORP (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0370414-A2 | Mechanical drive between parallel shafts, especially in apparatus displaying advertisements through rotary bodies forming together different advertisements sequentially | CENTRO STILE DESIGN S.r.l. (IT) | 1990-05-30 | — | — | EP | claimed |
| US-4436474-A | Selecting articles from an array thereof | WESTERN ELECTRIC CO., INC. (US) | 1984-03-13 | — | — | US | claimed |
| US-4266117-A | Self-ventilating infra-red ray heater | ECONORAY, INC. (US) | 1981-05-05 | — | — | US | claimed |
| US-4259667-A | Information interchange between an intelligent operator, indicia bearing documents, and responsive apparatus | WEBER HAROLD J | 1981-03-31 | — | — | US | claimed |
| US-4050405-A | Single-housing multi-trumpet air horn | MIDLAND-ROSS CORPORATION (US) | 1977-09-27 | — | — | US | claimed |
| US-4021931-A | Air circulating apparatus for floating material in web form | MIDLAND-ROSS CORPORATION (US) | 1977-05-10 | — | — | US | claimed |
| US-3958683-A | Conveyor system including article regrouping apparatus | MIDLAND-ROSS CORPORATION (US) | 1976-05-25 | — | — | US | claimed |