Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506633 | 0.83 | GPR84 (0.64) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL1506632 | 0.83 | GPR84 (0.64) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL6561695 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 | |
| Potassium Ion SCHEMBL7196538 | 0.79 | GPR84 (0.63) | GPR84FFAR1CA2NFKB1CA1 | |
| SCHEMBL830879 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 | |
| SCHEMBL515157 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 | |
| Potassium Ion SCHEMBL8442228 | 0.79 | GPR84 (0.63) | GPR84FFAR1CA2NFKB1CA1 | |
| SCHEMBL10913274 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 | |
| SCHEMBL9355567 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 | |
| SCHEMBL29800325 | 0.79 | CA2 (0.64) | GPR84FFAR1CA2NFKB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612161-B | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110612161-A | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2019-12-24 | — | — | CN | disclosed |