Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29762963 | 1.00 | IDO1 (0.44) | IDO1PDE2AMPLPTPN5ORAI1 | |
| SCHEMBL31550192 | 0.82 | ALOX15 (0.36) | IDO1PDE2ATSHRRXRAGRIN1 | |
| SCHEMBL607667 | 0.81 | PDE2A (0.46) | IDO1PDE2AMPLPTPN5TSHR | |
| SCHEMBL29453079 | 0.81 | PDE2A (0.46) | IDO1PDE2AMPLPTPN5TSHR | |
| SCHEMBL29637726 | 0.80 | PTPN5 (0.41) | PTPN5TSHRMAPK1MEN1KMT2A | |
| SCHEMBL7863398 | 0.80 | PTPN5 (0.41) | PTPN5TSHRMAPK1MEN1KMT2A | |
| SCHEMBL419718 | 0.79 | ALDH1A1 (0.41) | TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL30104741 | 0.79 | ALDH1A1 (0.41) | TSHRMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL12614768 | 0.79 | PDE2A (0.39) | IDO1PDE2AMPLPTPN5TDO2 | |
| SCHEMBL2147584 | 0.77 | PDE2A (0.50) | IDO1PDE2AMPLPTPN5TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543319-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | Johnson Matthey Public Limited Company (GB) | 2019-09-25 | — | — | EP | claimed |
| US-20140120626-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2014-05-01 | — | — | US | claimed |
| EP-2707465-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | Johnson Matthey Public Limited Company (GB) | 2014-03-19 | — | — | EP | claimed |
| WO-2012153132-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-11-15 | — | — | WO | claimed |
| US-4155940-A | M-Bromo-benzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | claimed |
| US-12509987-B2 | Continuous characterization and communication of chemical tracer | Patina IP LLC (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-12441703-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-10-14 | — | — | US | disclosed |
| EP-4267574-B1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| EP-0742010-A2 | Benzoquinolin-3-ones to inhibit bone loss | ELI LILLY AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0733365-A2 | Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer | ELI LILLY AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5550134-A | ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1996023783-A1 | INDOLE DERIVATIVES AS 5-HT RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM PLC (GB) | 1996-08-08 | — | — | WO | disclosed |
| EP-0493650-A1 | Fluorinated acetylene-containing aromatic amines and diamines | National Starch and Chemical Investment Holding Corporation (US) | 1992-07-08 | — | — | EP | disclosed |
| US-5107026-A | Fluorinated acetylene-containing aromatic amines and diamines | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-4155940-A | M-Bromo-benzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
| US-4155940-A | M-Bromo-benzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT1, PRMT5, PRMT6 | IDO1 2735/4885PDE2A 1640/4885MPL 3935/4885 |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | PRMT5, PRMT1, PRMT9 | IDO1 2821/4885PDE2A 856/4885MPL 2323/4885 |
| US-12509987-B2 | Continuous characterization and communication of chemical tracer | EXOSC10, CD69, FABP3 | IDO1 3837/4885PDE2A 2369/4885MPL 3001/4885 |
| US-12441703-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | IDO1 3851/4885PDE2A 407/4885MPL 4323/4885 |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | OPRM1, CYP1A1, CYP3A4 | IDO1 805/4885PDE2A 1875/4885MPL 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.