Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.53 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.53 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 3/20 | 0.48 |
| ▸ | CHAT | P28329 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356356 | 0.93 | KMT2A (0.52) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL2858719 | 0.93 | KMT2A (0.52) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL29401264 | 0.92 | KMT2A (0.71) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL15276051 | 0.92 | KMT2A (0.71) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL28414211 | 0.91 | KMT2A (0.69) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL12177938 | 0.90 | KMT2A (0.66) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL12177901 | 0.90 | KMT2A (0.66) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL12177978 | 0.86 | MEN1 (0.68) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL29425663 | 0.86 | SNCA (0.45) | THRBKMT2AMEN1SENP3SENP2 | |
| SCHEMBL2862763 | 0.86 | SNCA (0.45) | THRBKMT2AMEN1SENP3SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801409-A | Cleaning composition | 宝洁公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111684056-A | Cleaning method | 宝洁公司 | 2020-09-18 | — | — | CN | disclosed |